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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"5S rRNA"”.
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Regulation of RNA polymerase III transcription by the ID1, ID2, ID3 and E47 proteins
… protein synthesis, including transfer (tRNA) and 5S ribosomal RNA (5S rRNA). Pol III transcription levels are increased in many cancers, as increased protein synthesis is required for tumour growth. Furthermore, it has been shown that a number of oncoproteins and tumour suppressor proteins …
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In vivo studies of repressors of RNA polymerase III transcription
… small but vital set of genes, including 5S rRNA and tRNAs. Pol III transcription has been shown to be upregulated in transformed and cancer cells, suggesting an important role in cell growth and proliferation. Its tight regulation is, therefore, fundamental for cell welfare, and a number …
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Die Rolle von eIF-5A und Kernaktin bei Kernexportprozessen
… TFIIIA ist ein Exportfaktor für die Oocyten-Typ 5S rRNA in Amphibien Oocyten und besitzt wie Rev ein Leucin-reiches NES. Aufgrund einer Analyse dieses RNA Exportweges konnte nun gezeigt werden, daß eIF-5A auch in diesem spezifischen Exportweg als Adapter wirkt, der das NES des TFIIIA mit dem …
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Computational Techniques Applied to RNA Structures and Bacterial Genomes
… of at least five additional pores in the 23S rRNA that range 1.0-1.5 nm in size. Examination of other RNAs identified 11 other RNA pores. Structurally, the PTC and other 23S rRNA pores are very similar, i.e. both are created from the packing of helices, but RNA bases in the latter do not …
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Novel Ribosome Biogenesis in the Lyme Disease Spirochete Borrelia burgdorferi
… from a spirochete and its role in processing rRNA transcripts from the unusual rRNA gene operons of Borrelia burgdorferi. In most bacteria, the three rRNA transcripts (16S, 23S, and 5S rRNAs) that form the ribosome are produced as a single transcript from an operon with minimal spacing between …
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Novel Ribosome Biogenesis in the Lyme Disease Spirochete Borrelia burgdorferi
… from a spirochete and its role in processing rRNA transcripts from the unusual rRNA gene operons of Borrelia burgdorferi. In most bacteria, the three rRNA transcripts (16S, 23S, and 5S rRNAs) that form the ribosome are produced as a single transcript from an operon with minimal spacing between …
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The regulation of RNA polymerase III transcription by protein kinase CK2
… RNA molecules such as transfer (tRNA) and 5S ribosomal RNA (5S rRNA). Indeed, recent evidence suggests that tRNAiMet production is limiting for translation and proliferation in some cell types. Therefore, the rate of pol III transcription plays a fundamental role in cellular growth and …
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Isolierung eines nukleären 60S Prä-Ribosoms, das ein Exportintermediat ins Zytoplasma darstellt
… aus den ribosomalen L-Proteinen, 27SB und 7S rRNA-Vorstufen und reifer 25S, 5.8S und 5S rRNA. Weiterhin enthält das 60S Prä-Ribosom mindestens 23 nichtribosomale Proteine, die überwiegend essentiell und evolutionär konserviert sind. Nachdem nug1 und nug2 ts Mutanten Defekte im 60S Export …
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DNA repair and genomic instability in yeast aging
… excise from chromosomal rDNA arrays, containing 35S and 5S rRNA genes. At each cell division, ERCs replicate via an origin of replication present in each rDNA repeat, accumulate asymmetrically in the mother cells due to their segregation bias, and ultimately cause nucleolar fragmentation and …
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Characterization of a single TRAM domain RNA-binding protein from the Antarctic methanogen Methanococcoides burtonii
… M. burtonii RNA with a preference for tRNA and 5S rRNA, and a potential binding motif was identified. In tRNA, the motif represented the C loop; a region that is conserved in tRNA from all domains of life and appears to be solvent exposed, potentially providing access for Ctr3 to bind. In 5S …
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Identification and characterization of the ribosomal RNA operons from Rhodobacter sphaeroides
… analysis has identified the 16S, 23S and 5S rRNAs, two tRNAs (ile and ala) in the 16S-23S spacer region, and an f-met tRNA immediately following the 5S rRNa gene of all three operons. The secondary structure of the rRNA and tRNA molecules present in the rRNA operons was deduced and …
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REPAIR AND EFFECTS OF THE 8-OXOG LESION IN DNA
… bp wrapping fragment from the Xenopus borealis 5S rRNA gene to form individual nucleosome core particles (NCP). The effect of nucleosome formation on chromium- mediated DNA damage and the efficiency of BER glycosylase cleavage of the lesion 8-oxoG were investigated. Base excision of 8-oxoG by …
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REPAIR AND EFFECTS OF THE 8-OXOG LESION IN DNA
… bp wrapping fragment from the Xenopus borealis 5S rRNA gene to form individual nucleosome core particles (NCP). The effect of nucleosome formation on chromium- mediated DNA damage and the efficiency of BER glycosylase cleavage of the lesion 8-oxoG were investigated. Base excision of 8-oxoG by …