Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"5HT"”.
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5HT 2 Rezeptor vermittelte Kontrolle des neonatalen medullären respiratorischen Netzwerks des Säugers
Der Serotonin 2B Rezeptor (5HT 2B Rezeptor) ist ein wichtiger Regulator während der Embryonalentwicklung. Eine Inaktivierung des 5HT 2B Gens führt zu embryonalen und früh postnatalem tot bei Mäusen (Nebigil et al. PNAS 97:9508-13, 2000). Bis jetzt wurde noch kein Nachweis für funktionelle 5HT 2B …
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Investigation of the intracellular pathways required for 5HT-induced mitogenesis and their role in pulmonary hypertension.
… death. The monoamine 5-hydroxytryptamine (5HT) has been implicated in the processes of pulmonary vasoconstriction and pulmonary artery remodelling that contribute to the development of the PAH. However, the signalling mechanisms utilised by 5HT that contribute to pulmonary vascular …
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Structural Determinants of Post-transcriptional Protein Regulation as Modulators of Monoamine Signaling
… (NE), dopamine (DA), and serotonin (5HT) were discovered in both the periphery and the brain. Due, in part, to the implication of monoamines in the etiology of a wide range of dysfunctions, the examination of their physiological functions became the subject of a considerable volume of …
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Modulation of the Serotonin Reuptake Transporter in RAW264.7 Macrophages
… SERT function, measured by assays of 3H-5HT uptake. The 5-HT uptake in RAW264.7 macrophages was more than 10-fold that of peritoneal macrophages, indicating that these cells are an excellent model for studying regulation of the SERT. Activation of macrophages with lipopolysaccharide (LPS) …
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Biogenic Amine Levels Correlate with Time of Day, Age, Light Cycle, and Aggressive State in the Flesh Fly, Sarcophaga crassipalpis
<p>The biogenic amines serotonin (5HT), dopamine (DA), and octopamine (OA) have been indicated in the regulation of behaviors, including aggression. The flesh fly, <em>Sarcophaga crassipalpis</em>, was used to investigate ontogenetic and circadian changes in amines and aggression. Heads of male …
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Serotonin (5-HT) Increases Olfactory Responsiveness in the Tobacco Hawkmoth Manduca sexta
… processing and perception and indicate that 5HT tunes the sensitivity of the olfactory system.
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CHRONIC LOW-LEVEL LEAD EXPOSURE AFFECTS THE MONOAMINERGIC SYSTEM IN THE MOUSE SUPERIOR OLIVARY COMPLEX
… exposure caused a significant decrease in VMAT2, 5HT, and DβH expression while VGLUT1, VGAT and VAChT showed no change. These results provide evidence that Pb exposure during development alters normal monoaminergic expression in the auditory brainstem.
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CHRONIC LOW-LEVEL LEAD EXPOSURE AFFECTS THE MONOAMINERGIC SYSTEM IN THE MOUSE SUPERIOR OLIVARY COMPLEX
… exposure caused a significant decrease in VMAT2, 5HT, and DβH expression while VGLUT1, VGAT and VAChT showed no change. These results provide evidence that Pb exposure during development alters normal monoaminergic expression in the auditory brainstem.
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Manipulation of second messengers by ectopic expression of receptors in transgenic Drosophila
… peptide receptor, GC-A, the Drosophila 5HT7Dro receptor, and the Drosophila 5HT1ADro receptor, under control of the UAS or heat-shock promoter. Tubules dissected from such flies were then demonstrated to show diuresis induced by application of rANP or 5HT, whereas controls showed no …
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An Investigation into Neuroendocrine Regulators of Excretory Organs in the Adult Disease-Vector Mosquito, Aedes aegypti
… anti-diuretic role, inhibiting DH31- and 5HT-stimulated secretion through the NOS/cGMP/PKG pathway. CAPA-mediated inhibition promotes V-type H+-ATPase (VA) disassembly, reducing the driving force of DH31-stimulated secretion. Post-blood feeding, DH31 peptides are immediately released into …
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Structure Activity Relationships for Intracellular Loop 2 of the 5HT1A Serotonin Receptor
… Relationships for Intracellular Loop 2 of the 5HT1A Serotonin Receptor</p> <p>Chairperson: Dr. Keith Parker </p> <p> The human (H) serotonin (5-hydroxytrptamine; 5HT) 1a receptor (R) has been implicated in various physiological processes such as mood regulation, vascular and temperature …
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Structure Activity Relationships for Intracellular Loop 2 of the 5HT1A Serotonin Receptor
… Relationships for Intracellular Loop 2 of the 5HT1A Serotonin Receptor</p> <p>Chairperson: Dr. Keith Parker </p> <p> The human (H) serotonin (5-hydroxytrptamine; 5HT) 1a receptor (R) has been implicated in various physiological processes such as mood regulation, vascular and temperature …
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Imunorreatividade à FMRF-amida no sistema nervoso central e na musculatura pediosa de Megalobulimus oblongus
… iônicos de K+ tipo S (sensíveis à serotonina (5HT)), hiperpolarizando a membrana celular e assim, aumentando o limiar para o desencadeamento do potencial de ação. A distribuição da imunorreatividade à FMRF-amida em M. oblongus foi investigada empregando-se a técnica imunohistoquímica com …
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5-HT1A receptor expression : Studies in postmortem tissue and characterisation of a model system.
… polymorphism in the promoter region of 5HT[1A] receptor C-1019G is also associated with depression and suicide. The nuclear DEAF-1 related (NUDR) protein represses the 5-HT[1A] promoter region hence regulating both 5-HT[1A] transcription and receptor expression. The project involved …
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Pathological changes in mesostriatal neurons in a PKC-gamma mutant rat
… dopaminergic cells of the SNC) and serotonin (in 5HT+ve cells of the dorsal raphe nuclei) were both significantly increased in AS/AGU (mutant) compared to the AS (control) rats aged 6 months and older. TH and 5-HT immunofluorescence levels were both significantly decreased in the striatum in the …