Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"5-HT7 receptor"”.
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Site-directed mutagenesis and molecular modeling studies of h5-HT7(a) receptor reveal important residues for binding and activation
… on knockout animals and using selective 5-HT7 receptor antagonists have provided strong support that the G-protein-coupled 5-HT7 receptor plays a role in the onset of depression. To better understand the process of ligand binding to and activation of the 5-HT7 receptor and which essential …
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Familiar Food-Induced Feeding Activation in C. Elegans
… by activating two distinct neural pathways. A 5-HT7 receptor activated the two motions mainly by acting in the two distinct pharyngeal motor neurons that are essential for food-induced feeding activation. Moreover, the results support that the serotonin receptor activated the two distinct neurons …
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The role of serotonin-2C receptors in the rat circadian system.
… of light information with activation of 5-HT2C receptors at night having a photo-mimetic effect. The studies described in this thesis aim to clarify the role of 5-HT2C receptors in the control of circadian rhythms in the rat model and compare their actions to light. The acute effects of 5-HT2C …
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Development of 'In vitro' intestinal models to study the pharmacology of drugs affecting the gastrointestinal tract in normal and diseased conditions. Development of a cell culture model for intestinal pharmacology.
Studies investigating the effect of 5-HT receptors mediating a response in the neonatal intestine have been limited. There are evidences that the development of new neurones continues past postnatal term and this suggests that receptors expression may differ during maturation. Thus, `in vitro¿ …
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Development of 'In vitro' intestinal models to study the pharmacology of drugs affecting the gastrointestinal tract in normal and diseased conditions. Development of a cell culture model for intestinal pharmacology.
Studies investigating the effect of 5-HT receptors mediating a response in the neonatal intestine have been limited. There are evidences that the development of new neurones continues past postnatal term and this suggests that receptors expression may differ during maturation. Thus, `in vitro¿ …
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Molecular Mechanisms of Serotonergic Signaling: Role in Neuronal Outgrowth and Receptor Oligomerization
Rolle des 5-HT7/G12 Signalwegs bei der Morpho- und Synaptogenese. Der Neurotransmitter Serotonin (5-Hydroxytryptamin oder 5-HT) moduliert, zusätzlich zu seiner Funktion als Neurotransmitter, verschiedene Aspekte der frühen neuronalen Differenzierung, einschließlich des Neuritenwachstums und der …