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Showing 1 to 1 of 1 for “"5-HT7(a) serotonin receptor, site-directed mutagenesis, binding, activation"”.

  1. Site-directed mutagenesis and molecular modeling studies of h5-HT7(a) receptor reveal important residues for binding and activation

    Serotonin (5-hydroxytryptamine, 5-HT) is a key neurotransmitter implicated in neuropsychiatric disturbance such as depression, anxiety and psychosis. Recent studies on knockout animals and using selective 5-HT7 receptor antagonists have provided strong support that the G-protein-coupled 5-HT7 …

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