Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"5-HT2AR receptor"”.
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Protein-Protein Interactions with Serotonin G Protein Coupled Receptors: Novel Targets for Neurotherapeutics Drug Discovery
G protein coupled receptors (GPCRs) are involved in many physiological processes and are important therapeutic targets for a variety of human health disorders. In fact, approximately 30% of current FDA-approved medications target GPCRs and that number is likely to continue to rise with current …
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Signal transduction by the 5-HT2A receptor and its H452Y polymorphic variant
The 5-HT2A receptor (5-HT2AR) is implicated in neuropsychiatric disorders such as schizophrenia and is thought to mediate the actions of a number of hallucinogenic and antipsychotic drugs. Additionally, certain polymorphic variants of the receptor, such as an allele resulting in substitution of …