Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 1 of 1 for “"5-HT1A-R off-target affinity"”.
-
Characterisation of novel alpha1-adrenoceptor ligands
… due to a lack of subtype selectivity and the 5-HT1A-R off-target affinity. In this study, computer-aided drug design, structure-activity relationship, and molecular pharmacology methods were used to identify α1A-AR subtype selective compounds with reduced 5-HT1A-R off-target affinity. In silico …