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Showing 1 to 6 of 6 for “"5-HMF"”.
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IN-VITRO METABOLISM AND PROTEIN BINDING OF 5-HMF, A POTENTIAL ANTISICKLING AGENT
<p>Purpose. 5-HMF is a potential antisickling agent forming a Schiff-adduct with hemoglobin (Hb). In-vitro studies were designed to identify the metabolic pathways of 5-HMF in human hepatic cytosol, to assess inter-species differences in its hepatic metabolism, and to predict in-vivo PK properties. …
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IN-VITRO PK/PD PROFILING AND MODELING OF THE ANTI-SICKLING AGENTS, 5-HYDROXYMETHYL FURFURAL (5-HMF) AND NOVEL SYNTHETIC ALLOSTERIC EFFECTORS OF HEMOGLOBIN (AEH) IN HUMAN WHOLE BLOOD
<p>Introduction. 5-HMF and novel INN-compounds are left-shifting AEH, shown to have anti-sickling action by forming transiently covalent Schiff-base adducts with hemoglobin (Hb), thereby increasing the Hb O2-affinity. They are hypothesized to be substrates for aldehyde dehydrogenase (ALDH) in the …
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Auswirkungen von hohem hydrostatischem Druck auf Schimmelpilze und die Synthese des Mycotoxins Patulin
… vollständig von 5-Hydroxymethylfuraldehyd (5-HMF), einem in Apfelsaft vorkommenden Zersetzungsprodukt von Kohlenhydraten, trennen. Die Wiederfindungsrate beträgt bei Patulin > 96 , bei 5-HMF ~ 80 Die Nachweisgrenze beider Substanzen ist 2 µg/l. Die Syntheserate von Patulin ist abhängig von dem …
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Implementing Solvothermally Synthesized Carbon Nanodots into Dye-Sensitized Solar Cells to Enhance External Quantum Efficiency in the Ultraviolet
… the production of 5 Hydroxymethylfurfural (5-HMF), is suspected by many researchers to form CNDs via aldol condensation. Despite the hydrothermal synthesis method being a facile method for 5-HMF production and condensation to form CNDs, it remains inefficient and requires dialysis as a means …
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Monitoring and characterization of yeasts behavior under fermentation processes using technometric approaches
… and 0.5% (v/v) 5-hydroxymethylfurfural (5-HMF) in batch fermentations with YPD as culture medium. MPCA and PLS-LOG allowed to evidence the different behavior of S288c comparing to PE-2 and CA11, and a higher impact caused by 1-butanol, furfural and 5-HMF in phenotypic and physiological …
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Developing Novel Conservative Treatments For 2 Endometrial Cancer By Targeting Aquaporin-1
… (Bumetanide derivatives AqB011 60 μM-100 μM, 5-HMF, 1mM, 5-PMFC 0.5 mM), and non-specific AQP4 modulators (IMD-0354 0.2 μM, TGN-020 3 μM). A wide range of dose of all drugs were tested and optimal doses causing 50% inhibition of invasion were identified. We found that AqB011 (80 μM) and 5-PMFC …