Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"5-Fluorocytosine"”.
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INVESTIGATION OF ANTIBIOFILM AND ANTIVIRULENCE ACTIVITY OF 5-FLUOROCYTOSINE IN ESCHERICHIA COLI
… and nucleobase/nucleoside analogues, such as 5-fluorocytosine and 5-fluorouracil, have been shown to possess antivirulence activity in Gram negative bacteria like Pseudomonas aeruginosa and Escherichia coli. In my PhD work, based on previous observation that pyrimidine nucleotide availability …
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Susceptibility Testing of Pathogenic Fungi With a Radiometric System
… agents evaluated were Amphotericin B, 5-fluorocytosine, Nystatin, Ketoconazole, Miconazole, Terconazole, and Itraconazole. The instrument used to measure amount of radioactive carbon dioxide generated by fungal metabolism of ¹⁴C-glucose in presence of antifungal agents was the Bactex 460. …
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Dual Targeting of Tumor Angiogenesis and Chemotherapy By Endostatin- Cytosine Deaminase-Uracil Phosphoribosyltransferase
… area, where it serves nontoxic prodrug 5-fluorocytosine (5-FC) enzymaticconversion reaction to anti-metabolite chemotherapy drug 5-fluorouracil (5-FU). Wedemonstrated that 5-FU concentration was highly increased in tumor sites, resultingin high level of endothelial cells and tumor cells …
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Glioma produced periostin attracts human neural stem cells
… glioma cells after application of the prodrug, 5-fluorocytosine (5-FC). To harness the chemotactic ability of POSTN as a tool to induce a strong bystander killer effect of brain tumors, we established the brain tumor animal model which was implanted with C6 cells and the increasing number of …
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Characteristic analysis of mobility inducers for neural stem cells
… effect by repetitive infusion of prodrug, 5-fluorocytosine (5-FC), reduced tumor mass with increasing number of CM-2-expressing cells. Transplanted group of CM-1-producing NIH 3T3 cells significantly extended survival time over 105 days than transplantation of glioma cells. PET imaging data …
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Suicide Gene therapy for Malignant Gilomas using Neural Stem Cells
INTRODUCTION: Despite advanced neurosurgical techniques and various multimodal therapeutic approach have been developed for malignant gliomas, these can not save the patients from the tumors due to infiltrating behavior of these glioma cells. Here, author investigated the possibility of treatment …
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Theoretical And Experimental Studies Of Noncovalent Metal Cation Binding And Base Pairing Interactions Of Cytosine And Modified Cytosines
… in this work are 5-methylcytosine (5MeC), 5-fluorocytosine (5FC), 5-bromocytosine (5BrC), 5-iodocytosine (5IC), 1-methylcytosine (1MeC), 5-fluoro-1-methylcytosine (1Me5FC), 5-bromo-1-methylcytosine (1Me5BrC), and 1,5-dimethylcytosine (15dMeC). Relative N3 proton affinities (PAs) of the …