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Showing 1 to 20 of 78 for “"5 year survival rate"”.

  1. Characterization of Cellular and Genomic Effects of 1,25-Dihydroxyvitamin D3 in Prostate Progenitor/Stem Cells

    Maund, Sophia LisetteWake Forest University2011

    … eradicated by surgery or radiation with a 100% 5-year survival rate. Late-stage prostate cancer is treated with hormone ablation therapy, but the 5-year survival rate drops to ~40% due to metastatic spread and/or development of androgen-independent prostate cancer. Even men whose prostate cancer …

    wfu Repository record

  2. TARGETED POLYMER NANOPARTICLES FOR THE DETECTION AND TREATMENT OF DISSEMINATED COLORECTAL CANCER IN VIVO

    McCabe, EleanorWake Forest University2018

    … cytoreductive surgery (CRS) has improved the 5-year survival rate of late-stage CRC patients from 12% to 51%. However, the survival rates of these patients have stagnated, which emphasizes the need for more innovative approaches to improve patient survival outcomes.

    wfu Repository record

  3. Investigating Metastatic Lineage In Colorectal Cancer By Single Cell Dna Sequencing

    Leung, Marco2017

    … colorectal cancer (mCRC) show only an 11% 5-year survival rate, compared to those without local or distant metastases (92% 5-year survival rate). Understanding the CRC tumor evolution may provide valuable insights on how to improve treatment in patients with mCRC. However, the genomic basis …

    uthsc Repository record

  4. A Review of Women with Epithelial Ovarian Carcinoma in a Middle-Income setting: Groote Schuur Hospital, Cape Town, South Africa: Demographics, Treatment and Outcomes of Patients between 2005 and 2015

    Loggenberg, FranciscaDepartment of Obstetrics and Gynaecology2024

    … for latestage disease and high recurrence rates. Ovarian Carcinoma ranks 8th amongst new cancer cases in women and accounts for 4.7% of reported cancer deaths.1 Women often present late with advanced disease of which the prognosis remains poor. The 5-year survival rate of stage 3 disease …

    cape-town Repository record

  5. 4D Ex Vivo Crispr/Cas9 Whole-Genome Screen to Identify Genes Regulating Lung Cancer Metastasis

    Plumer, Alexandria, <p><a href="https://orcid.org/0000-0002-7889-7378">0000-0002-7889-7378</a></p>2021

    <p>Metastatic lung cancer has a 5-year survival rate of 5%. Lung cancers tend to be asymptomatic until late stages, and almost 90% are not diagnosed until they are advanced. Metastases are very rare events, often initiated by a single cell from a primary tumor into a new niche at a distant …

    uthsc Repository record

  6. Comparison of Survival between Patients with Serous Fallopian Tube carcinoma and Serous Adenocarcinoma of the Ovary

    이, 경미2011

    … had no enough evidence. So we sought to compare survival trends between fallopian tube carcinoma and ovarian carcinoma patients in a matched, case–control comparison. Fifteen patients with serous fallopian tubal carcinoma were identified on Ajou university medical center from September 1994 to …

    ajou Repository record

  7. Novel Neuroblastoma Differentiating Agents

    Laguera, BreanaTexas State University2020

    … pediatric cancer. In high-risk patients, the 5-year survival rate is 40-50% after treatment. The differentiation therapy with retinoic acid (RA) is at the forefront of approaches to treat neuroblastoma; however, more than half of patients experience recurrence suggesting resistance to RA. There …

    texas-state Repository record

  8. Time-Restricted Eating and Prebiotic Supplementation in Young Adult Pediatric Cancer Survivors

    Kate Cares (13716496)2025

    … however, over the past several decades, survival rates have increased from 58% in the 1970’s to a current 5-year survival rate of 85%. Despite long term remission, PCS experience chronic disease at an earlier age than matched controls which may be a result of increased biological aging, …

    uic

  9. MicroRNAs in Pancreatic Ductal Adenocarcinoma: New Approaches For Better Diagnosis And Therapy

    Mortoglou, MariaUniversity of Westminster2024

    … aggressive malignancies with less than an 8% 5-year survival rate, which has remained unchanged over the last 50 years. Early detection is particularly difficult due to the lack of disease-specific symptoms and reliable diagnostic biomarkers. Multimodality treatment including chemotherapy, …

    westminster Repository record

  10. Outcome of Severe Aplastic Anemia Treated with Immunosuppressive Therapy Compared with Bone Marrow Transplantation

    김, 형일2011

    BACKGROUND: We compared response rates and survival after allogeneic bone marrow transplantation (BMT) or immunosuppressive treatment in severe aplastic anemia (SAA) and identified prognostic factors related with survival. METHODS: Medical data of SAA patients who treated with BMT or …

    ajou Repository record

  11. Leveraging Single Cell Technologies For The Characterization and Treatment of Refractory Pancreatic Cancer

    Monberg, Maria, https://orcid.org/ <p><strong>0000-0002-5643-0232</strong></p>2022

    … a highly lethal malignancy with a mere 11% 5-year survival rate, this dissertation focuses on first questioning the assumptions of the most basic models used to study PDAC via multimodal single-cell characterization methods at multiple levels of biological organization (scCNVseq and snATACseq …

    uthsc Repository record

  12. Mechanisms Underlying Alcohol-Mediated Cellular Injury In Esophageal Keratinocytes

    Modayur Chandramouleeswaran, Prasanna Venkata Ramanan2019

    … resistance to therapy has resulted in a poor 5-year survival rate of 20%. Alcohol consumption is a major environmental risk factor for developing ESCC. Acetaldehyde, a by-product of alcohol metabolism is a potent human carcinogen. Furthermore, single nucleotide polymorphisms (SNPs) in the …

    penn Repository record

  13. Understanding Young Adult Survivors of Childhood Cancers’ Participation in Late Effects Screening: A Mixed Methods Approach

    Mantlo, Kristen Trost2020

    … childhood cancers have helped to increase the 5-year survival rate from 56% in the early 1970s to approximately 80-85% in the early 2000s (Greenlee, Murray, Bolden, & Wingo, 2000; Hampton, 2005). Treatment modalities such as chemotherapy and radiation have led to many serious long-term side …

    odu Repository record

  14. Understanding and Targeting the FGF-2/S6K2 Signal Pathway in Small Cell Lung Cancer Towards the Development of Novel Anti-Cancer Treatments.

    Dunnett, Louise EUniversity of Essex2020

    … late 1980’s SCLC has a poor prognosis with a 5 year survival rate of only 5%, highlighting the need for novel therapeutic intervention. This pathway is initiated by Fibroblast Growth Factor 2 (FGF-2) binding its cognate receptor, Fibroblast Growth Factor Receptor 1 (FGFR-1). Downstream of …

    essex Repository record

  15. Analysis of Neurocognitive Elements of Attention Following Chemotherapy Treatment

    Grosch, Maria Catherine2013

    … approximately 123 out of 100,000 women per year in the United States, with 207,090 new cases estimated each year (Altekruse et al., 2010). Adjuvant chemotherapy has become a staple of care to improve long-term outcomes for several types of breast cancers (de Boer, Taskila, Ojajärvi, van …

    utswmed Repository record

  16. Descriptive epidemiology and outcome of patients with intraductal papillary mucinous neoplasm (IPMN): a population-based comparison to pancreatic adenocarcinoma and review of literature.

    Advitya MalhotraThe University of Texas Medical Branch2009

    … (67.0 vs. 70.1, P<.0001). The overall 5-year survival was 8.8% for IPMN (median, 5 months) and 3.7% for PA (median, 4 months, P < .0001). Patients with unresected IPMN had a 5-year survival rate of 4.2% compared to 2.2% in patients with unresected PA (P < .0001). Surgical resection was a …

    utmb Repository record

  17. Inhibiting metastatic potential: an analysis of migratory body formation in chondrosarcoma

    Ganguly, A.Middlesex University2025

    … 70% of cases reported affecting patients of 40 years and above. While CHS has an optimistic 5-year survival rate of 75.2%, this can depend greatly on the accuracy and time of diagnosis, histological grade, and subtype. Metastasis which often leads to chemoresistance have been primary …

    middlesex

  18. Fruit and vegetable intake and quality of life among breast cancer survivors

    Cheung, Hoi Ting HelenUniversity of Illinois at Urbana-Champaign2019

    … detection and treatment, survivors now have a 5-year survival rate > 90%. This has led to a shift in focus to improving not only survival, but also health-related quality of life (HR-QoL) after diagnosis, including physical, social, emotional, functional, and general well-being. High fruit and …

    uiuc Repository record

  19. The Effects of Tarsh Overexpression on Lung Carcinomas

    Kim, Young2018

    … it has proven difficult to control. The 5-year survival rate has been shown to be only 15.9%, despite the advances made in terms of diagnosis and treatment. Therefore, we are faced with the problem of finding more effective methods that allow for an earlier diagnosis and the improved …

    vcu Repository record

  20. A Novel Syndecan-1 Targeted Therapeutic Antibody Inhibits Macropinocytosis and Induces Anti-Tumor Immunity in Pancreatic Cancer

    Yang, Zecheng2026

    … of the deadliest malignancies, with an overall 5-year survival rate of only 13%. Given the prevalence of oncogenic <em>KRAS</em> mutations (<em>KRAS*</em>) and their role in PDAC development and growth, therapeutic strategies to quench KRAS*-driven malignant progression are urgently needed to …

    uthsc Repository record

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