Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 36 for “"5’-AMP"”.
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Uptake and Metabolism of 5’-Amp In The Erythrocyte Play Key Roles In The 5’-Amp Induced Model of Deep Hypometabolism
<p>UPTAKE AND METABOLISM OF 5’-AMP IN THE ERYTHROCYTE PLAY KEY ROLES IN THE 5’-AMP INDUCED MODEL OF DEEP HYPOMETABOLISM</p> <p>Publication No. ________</p> <p>Isadora Susan Daniels, B.A.</p> <p>Supervisory Professor: Cheng Chi Lee, Ph.D.</p> <p>Mechanisms that initiate and control the natural …
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The Physiological and Biochemical Understanding of 5’-Amp Induced Deep Hypometabolism
… via an injection of adenosine monophosphate (5’-AMP) followed by placement in an ambient temperature (Ta) around 15oC currently can last about 3-9 hours. While we have insight into how 5’-AMP induced hypometabolism is initiated, it remains unclear how arousal from hypometabolism is controlled. …
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The effect of protein and hydrogen ion concentration on the activity of rabbit muscle 5'-amp aminohydrolase
Thesis (M.S.)--Michigan State University. Dept. of Biochemistry, 1971
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Bacterial biodegradation of soluble crude oil hydrocarbons and the influence of protists in simulated arctic seawater and sea ice
<p>With expected increases in vessel traffic, drilling, and exploration for petroleum and natural gas, the potential for an Arctic oil spill is heightened, yet knowledge of contaminant fate and behavior is limited in this environment. With challenging conditions in the Arctic and limited equipment …
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The relationship between the two forms of glycogen phosphorylase in Dictyostelium discoideum
… phosphorylase. The inactive ’b’ form requires 5'AMP for activity and is present in early development, whereas the active ’a’ form is 5'AMP independent and is present in late development. Polyclonal antibodies raised to purified forms of the enzyme show low cross-reactivity. The anti-’a’ is …
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Development of biotin protein ligase inhibitors from Staphylococcus aureus as new antibiotics
… reaction of biotin and ATP to give biotinyl-5’-AMP 1.03, which then activates a number of biotin dependent enzymes that are critical to cell survival. Research undertaken in this thesis highlights strategies to selectively inhibit Staphylococcus aureus biotin protein ligase (SaBPL) over the …
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The relationship between two forms of glycogen phosphorylase in Dictyostelium discoideum
… is independent of 5′adenosine monophosphate (5′AMP) while the activity of the ’b' form (the inactive form) is 5′AMP dependent, The two forms are developmentally regulated. Polyclortal antibodies raised to the purified forms of this enzyme show low cross reactivity. The anti-’a' antiserum reacts …
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The "atypical" protein kinase, SsoPK5, an archaeal member of the piD261/Bud32 subfamily
… SsoPK5 is activated by ADP-ribose and 5′-AMP. Activation was observed when SsoPK5 was stabilized by ATP or a nonhydrolytic analogue, such as β,γ- methylene adenosine 5′-triphosphate (AMP-PCP). Activation was not a result of phosphoryl transfer nor hydrolytic breakdown of ATP or 5′-AMP. …
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Regulation of glycogen phosphorylase genes in Dictyostelium discoideum
… early in development, and is dependent upon 5’ AMP as a positive allosteric modifier; glycogen phosphorylase 2 (gp-2) activity peaks late in development and is independent of 5° AMP. I showed that these two glycogen phosphorylase activities are associated with unique proteins that are the …
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The Role of 5' Nucleotidase in the Regulation of Morphogenesis in Dictyostelium Discoideum
… that shows high substrate specificity to 5'AMP. The enzyme has received considerable attention in the past because of the critical role played by cyclic AMP in cell differentiation in this organism. Degradation of cAMP by cAMP phosphodiesterase (PDE) produces 5'AMP, the substrate of 5NU. …
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AMP- Activated Protein Kinase (AMPK) Activation for the Treatment of Mitochondrial Disease
… there is a decrease in ETC activity. 5' AMP-activated protein kinase (AMPK) is a kinase that can initiate mitochondrial biogenesis and mitophagy. We hypothesized that treating cells harbouring low numbers of mtDNA with an AMPK activator (5-Aminoimidazole-4-carboxamide ribonucleoside; …
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ΚΙΝΑΣΗ ΤΗΣ ΦΩΣΦΟΡΥΛΑΣΗΣ ΑΠΟ ΛΕΙΟ ΜΥΙΚΟ ΙΣΤΟ ΣΤΟΜΑΧΙΟΥ ΚΟΤΑΣ: ΑΠΟΜΟΝΩΣΗ ΚΑΙ ΜΕΛΕΤΗ ΤΩΝ ΚΑΤΑΛΥΤΙΚΩΝ ΚΑΙ ΔΟΜΙΚΩΝ ΙΔΙΟΤΗΤΩΝ ΤΗΣ
… INVOLVING AMMONIUM SULFATE FRACTIONATION 5'-AMP SEPHAROSE 4B AFFINITY CHROMATOGRAPHY COLUMN AND ULTRACENTRIFUGATION INGLYCEROL GRADIENT DENSITY CHICKEN GIZZARD PHOSPHORYLASE KINASE PRESENTS DIFFERENT STRUCTURAL AND CATALYTIC PROPERTIES IN DELATION TO THOSE FOUND FOR THE RABBIT SKELETAL MUSCLE …
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Investigating the Biological Effects of Rosemary (Rosmarinus officinalis L.) Extract on Skeletal Muscle Glucose Uptake
… to insulin resistance (IR). Activation of 5’ AMP-activated kinase (AMPK) is viewed as a targeted approach to counteract IR. Rosemary extract (RE) has been reported to decrease blood glucose levels but its effects on SKM are not known. We hypothesized that RE acts directly on SKM to increase …
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Molekulare und funktionelle Analyse der Drosophila-Mutante löchrig
… P-Elementes in einem Intron des Drosophila-g-5'-AMP-aktivierten Proteinkinase- (AMPK)-Gens. Die verschiedenen Spleißprodukte des loe Gens kodieren für die regulatorische g-Untereinheit des AMPK-Komplexes, der , aktiviert durch 5'AMP, energieintensive Prozesse negativ reguliert. Die Spleißform …
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Effects of Cisplatin Analog Size on the Reaction with DNA Bases
… triamine] were synthesized and their effects on AMP and GMP were studied using NMR spectroscopy. The experiments were conducted to examine the effects of bulk on 5’-GMP and 5’-AMP. The results suggest that bulk slows down the reaction with AMP more than with that of GMP. The order of reactivity …
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Understanding the Contribution of Meaningful Processing to the Testing Effect
The testing effect is an interesting phenomenon, with a wealth of support for its robustness. The basic idea is that attempting to learn something to retain over time is more fruitful when items are retrieved from memory or tested, than when items are restudied. This area of research has seen much …
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Corporate governance of state-owned enterprises: a theoretical perspective
This thesis rethinks the conceptualization and corporate governance (CG) of fully State-owned enterprises (SOEs) from a theoretical perspective. It contributes to the renewed efforts to gain a better understanding of the governance of these complex organizations that stand between the market and …
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The impact of carbohydrate ingestion on the regulation of fat oxidation following exercise
… of acety bCoA carboxylase (ACC), 5'AMP-activated protein klnase (AMPK) and hormone sensitive lipase (HSL) increased with exercise (p<0.05). ACC and AMPK phosphorylation in the CHO trial was lower at 1 h post than in the PLA trial (pc0.05). HSL phosphorylation remained above baseline …
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Study of the androgenic activity of the regenerating adrenal cortex.
The androgenic function of the adrenal cortex has been studied in adult male rats; circulating androgens were assessed through sexual accessory organ weights and zinc 65 uptake by the dorsolateral prostate. Acclimated intact and castrated animals were used as well as animals with regenerating …
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Studies of the NAD metabolism of Haemophilus influenzae
… was inhibited by adenine nucleotides _ and 5'-AMP, at 20 μM, abolished the negative cooperativity of the enzyme. The enzyme was determined to possess excitation and emission maxima at 286 and 337 nm, respectively, indicative of the presence of tryptophan. The fluorescence of the enzyme was …
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