Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"5'-adenosine monophosphate"”.
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ΜΕΛΕΤΗ ΣΥΠΛΟΚΩΝ ΜΕΤΑΛΛΙΚΩΝ ΙΟΝΤΩΝ ΜΕ 5' - ΑΔΕΝΟΣΙΝΟΜΟΝΟΦΩΣΦΟΡΙΚΟ ΟΞΥ, 6-ΜΕΡΚΑΠΤΟΠΟΥΡΙΝΗ ΚΑΙ ΤΟ ΡΙΒΟΣΙΔΙΟ ΤΗΣ ΚΑΙ 8-ΑΖΑΠΟΥΡΙΝΕΣ
IN THIS THESIS THE INTERACTION OF METAL IONS WITH ADENOSINE MONOPHOSPHATE, 6-MERCAPTOPURINE AND ITS RIBOSIDE - ANTICANCER DRUGS - AND 8-AZAPURINES IS INVESTIGATED. WE HAVE PREPARED THE COMPLEXES OF 5'- ADENOSINE MONOPHOSPHATE WITH MN2+, FE2+, ZN2+, PB2+, CD2+, PD2+, CE3+, PR3+, SM3+, TB3+, MO2 2+. …
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A Study of the Adrenergic Receptors in Mammalian Tracheal Smooth Muscle
… cortisol, no increase in tissue cyclic 3‘,5'-adenosine monophosphate (cyclic AMP) levels was found over those levels measured in tracheas incubated with sodium succinate as a control. It was concluded that, under the conditions studied, the mechanical activity produced by catecholamines on …
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The relationship between two forms of glycogen phosphorylase in Dictyostelium discoideum
… ’a' form (the active form) is independent of 5′adenosine monophosphate (5′AMP) while the activity of the ’b' form (the inactive form) is 5′AMP dependent, The two forms are developmentally regulated. Polyclortal antibodies raised to the purified forms of this enzyme show low cross reactivity. The …
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Radiation Sensitization of Breast Cancer Cells by Vitamin D Through the Promotion of Autophagic Cell Death
… were able to demonstrate a potential role of 5' adenosine monophosphate-activated protein kinase in the sensitization of breast tumor cells to radiation by vitamin D3 as well as cytotoxic autophagy.
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Anthrax toxin effects on B lymphocyte function
… adenylyl cyclase that forms 3’,5’-adenosine monophosphate (cAMP) from adenosine triphosphate (ATP). This enzymatic reaction causes an increase in intracellular cyclic AMP (cAMP) in host cells. As cAMP is a prominent second messenger in cellular signaling, edema toxin has a wide …
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Skeletal Muscle Protein Turnover During Cancer Cachexia In the Apc<sup>min/+</sup> Mouse
… in IGF-1 and possible inhibition related to 5`-adenosine monophosphate-activated protein kinase (AMPK) activation. Specific aim 2 examined the regulation of protein degradation during the progression of cancer cachexia. Proteasomal regulated protein degradation was induced during initial stages …
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Regulation of AMPA receptor acetylation and translation by SIRT2 and AMPK: the molecular mechanisms and implications in memory formation
… through two different signaling pathways, 5' adenosine monophosphate-activated protein kinase (AMPK) and sirtuin 2 (SIRT2), are described. It is shown that SIRT2, a NAD+-dependent protein deacetylase, directly controls AMPAR stability by regulating AMPAR acetylation. For the first time, we …
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Uptake and Metabolism of 5’-Amp In The Erythrocyte Play Key Roles In The 5’-Amp Induced Model of Deep Hypometabolism
… hypometabolism (DH) initiated by uptake of 5’-adenosine monophosphate (5’-AMP) into erythrocytes. Mice enter DH when given a high dose of 5’-AMP and the body cools readily. Influx of 5’-AMP appears to inhibit thermoregulatory control. In a 15°C environment, mice injected with 5’-AMP (0.5 mg/gw) …
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The psychopharmacogenetics of ethanol and its relation to brain catecholamines
… 2.) ethanol’s action on brain cyclic 3′, 5′-adenosine monophosphate; 3.) the correlation between alcohol preference and brain catecholamine measures; 4.) the effects of drugs, which have adrenergic action, on the behavioral response to ethanol and; 5.) the theory and evidence for the …
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Effects of dietary stimulators of metabolism and mitochondrial biogenesis in vitro and in vivo: Implications for metabolic disease
Background: Commercially available dietary products advertised to promote weight loss are an under researched but heavily purchased commodity in the United States. Despite only limited evidence, interest in dietary supplements continues to increase. Obesity is an increasingly prevalent and …