Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"5' UTR"”.
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Strucutre-function studies of the venezuelan equine encephalitis virus 5'UTR promoter element and its role in attenuation of the virus
… encoded by the 5’ \r\nUntranslated Region (5’UTR), in regulating virus replication and attenuation of \r\nVenezuelan equine encephalitis virus (VEEV) is described. VEEV is one of the \r\npathogenic members of the Alphavirus genus in the Togaviridae family. VEEV \r\ninfection causes …
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Analysis of the Role of EIF5A in Mammalian Translation
… regulators of MYC that function through the 5' UTR of the transcript, we performed a fluorescent reporter-coupled genome-scale CRISPR/Cas9-mediated loss of function screen. Analysis of screening data identified eukaryotic initiation factor 5A (EIF5A) as novel regulator of MYC translation. eIF5A …
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Characterization of an Orphan Riboswitch: Identification of a Metal-Sensing Regulatory RNA
… ykoK RNA element due to its location in the 5' UTR of the B. subtilis ykoK (mgtE) gene, which appears to be a magnesium transporter. Therefore, the possibility that this RNA senses magnesium levels was explored. The data revealed that the RNA element imparts magnesium-responsive regulation to …
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Targeting transcriptional and translational mechanisms to enhance utrophin A expression as a therapy for Duchenne muscular dystrophy
… integrity and progressive muscle wasting. Utrophin is the autosomal homologue of dystrophin and is present in skeletal muscles of DMD patients, although its expression is primarily restricted to the neuromuscular junction of mature skeletal muscle fibers. Enhancing expression of utrophin in …
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BIOCHEMICAL AND MOLECULAR CHARACTERIZATION OF RAFFINOSE FAMILY OLIGOSACCHARIDE (RFO) BIOSYNTHESIS IN LENTIL (Lens culinaris Medik.)
… clone LcSTS was isolated that is 2669 bp long (5'UTR - 30bp, ORF - 2559, 3'UTR 80 bp followed by polyA) coding for 853 amino acids with predicted molecular weight of 96 kDa. RNA gel blot and qPCR analyses showed maximum accumulation of LcSTS transcript at 26 and 24 DAF respectively. Stachyose and …