Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 85 for “"3R"”.
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The asymmetric synthesis of (2S,3R)-capreomycidine and the total synthesis of capreomycin IB
… of the non-proteinogenic amino acid (2S,3R)-capreomycidine is presented. The synthesis features a novel aluminum enolate-aldimine reaction with a chiral glycinate, which sets both stereocenters. A concise and high-yielding approach to the unnatural amino acid (2S,3S)-β-hydroxyornithine is …
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Disseny d'un projecte d'aplicació de les TIC a través de Moodle per a l'alumnat de Geografia i Història de 3r d'ESO
… TIC en l'assignatura de Geografia i Història de 3r d'ESO mitjançant una metodologia b-learning i l'ús del Moodle.
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Structural Polymorphism in Tau Filaments: An Implication for Neurodegenerative Diseases
… half of the tau isoforms have three repeats (3R tau), whereas the other half has four repeats (4R tau).</p> <p>Site-directed spin labeling of recombinant tau in conjunction with electron paramagnetic resonance spectroscopy was used to obtain structural insights into tau filaments. The studies …
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The Relative Efficiency of Two Strategies For Conducting Cognitive Task Analysis
… (GS) for an approach that was designated the "3i+3r method." A fourth expert was given a full CTA interview and that experts report was then given to a fifth and sixth SME to review and correct. The final result was designated the "1i+3r GS." This method required significantly less time from the …
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Insulin-like growth factor binding protein-3 (IGFBP-3) plays an essential role in cellular senescence: molecular and clinical implications.
… Our studies demonstrate IGFBP-3 and novel IGFBP-3R can induce senescence in young fibroblasts, while suppression of IGFBP-3 in pre-senescent fibroblasts, can delay the onset of replicative senescence. We identified ROS accumulation in IGFBP-3/IGFBP-R-induced senescent cells which we speculated …
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Syntheses, bioactivities and conformations of peptidomimetics containing 2,3-methanoamino acids
… giving four peptidomimetics, namely F$\{$2S,3R-cyclo-M$\}$RF-NH$\sb2$, F$\{$2R,3S-cyclo-M$\}$RF-NH$\sb2$, F$\{$2S,3S-cyclo-M$\}$RF-NH$\sb2$ and F$\{$2R,3R-cyclo-M$\}$RF-NH$\sb2$. A peptidomimetic containing two 2,3-methanoamino acids substituted in the 2 and 4 positions (ie …
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Mechanism of TNF-α cytotoxicity in a leukemia virus transformation model
… with A-MuLV, these cells gave rise to a clone (3R.1) which was found to be insensitive to TNF-α and another clone (6R.1) which had an increased sensitivity to TNF-α. The differential cytotoxicity was observed when cells were treated with TNF-α, for 18 hr, at 0 to 100 units/ml, at 37°C. The …
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Guanidino-aryl substituted enol lactones: Selective and potent mechanism-based inhibitors of trypsin-like serine proteases
… $\alpha$-benzamido substituted analogs (3R*,4R*) 3-benzamido-4-(guanidinophenyl)-6-methylidene tetrahydro-2-pyranone (7) and (3R*,4R*) 3-benzamido-4-(4-guanidinophenyl)-6(E)-iodomethylidene tetrahydro-2-pyranone (8).
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Hormetic dietary phytochemicals from Western Canadian plants: Identification, characterization and mechanistic insights
… and weaker support for the compounds (3R,8S)-falcarindiol, 6-isovaleryl-umbelliferone (6-IVU) and (Z)-ligustilide. Additionally, transcript level analyses supported a role for the aryl-hydrocarbon receptor in QR-activation by (3R,8S)-falcarindiol, (Z)-ligustilide, (R)-sulforaphane, …
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Stereochemical aspects of virginiamycin biosynthesis: biosynthesis of antibiotic A33853
… into virginiamycin M₁. (2S)-serine and (2S,3R)-[3-³H] serine were found to be precursors, thus giving evidence of stereochemical control in the formation of the oxazole moiety. This information allowed for postulation of a ring closure pathway. Stereochemical investigations were also carried …
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Synthesis, design and characterization of a distributed feedback grating based non-linear optical chemosensor
Current optical chemosensors that operate by a 3R sensing approach - recognize, relay and report -- generate a measurable luminescent signal in the presence of targeted analyte. However, the advancement of chemical sensing into the micro- and nanoscale regimes necessitates the development of new …
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An Electron Microscopy Study of Modulated Microstructures in Beta Nickel-Aluminum and Other Alloys
… investigations have been carried out on the 3R, 7R, Ni(,5)Al(,3) and Ni(,3)Al phases in the same alloy in the as-quenched condition or after aging at temperatures in the range 300(DEGREES)-850(DEGREES)C, and on Cu-Be, Cu-Zn and Cu-Al-Ni alloys.
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Dessimetrização e enriquecimento enantiomérico de derivados do triciclo[5.2.1.0 2,6] decano através de enzimas e de indutores quirais. Preparação dos respectivos pseudopeptídeos restritos
… > 99%) foram sintetizados a partir do meso- exo-(3R,5S)-3,5-dihidróximetilenotriciclo[5,2.1.0²,⁶]decano com altos rendimentos, usando catálise enzimática (lipases) em reações de transesterificação. A resolução do respectivo diéster racêmico através da hidrólise catalisada com esterase (PLE) não …
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A New Synthesis of enantiopure C-3-substituted Glutamates by Utilization of Ortho Ester protected (S)-Pyroglutamic acid
… =phenyl,4-chlorophenyl,biphenyl,naphthyl) are (2S,3R)-configurated). The C-3-substituted ortho ester derivatives were completely deprotected to yield the C-3-substituted pyroglutamates (R=ethyl,phenyl,4-chlorophenyl,naphthyl). Finally, ring opening reaction via route A-2 lead to the desired …
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Crosstalk suppression techniques for multi-channel regeneration based on fiber optic parametic amplifier
… growth of transmission speed and capacity.2R or 3R regeneration can refine the degraded signal and improve transmission performance. 2R stands for reamplifying and reshaping the signal, and 3R adds retiming of the signal. Conventionally, electrical repeaters are used for the regenerations. In …
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Desempenho operacional de um conjunto trator-semeadora-adubadora em plantio direto da soja
… fatorial 3 x 4, com três marchas reduzidas (2R, 3R e 4R) e quatro rotações no motor, (1600, 1800, 2000 e 2200 rpm) em delineamento em blocos casualizados, com quatro repetições, totalizando 48 unidades experimentais. O desempenho do conjunto foi avaliado por meio da demanda energética e qualidade …
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Genetics of reactions to soybean mosaic virus in soybean
… either resistant or necrotic parents segregated 3R:1S and 3N:1S, respectively. F₂-derived F₃ progenies from R x S crosses exhibited an F₂ genotypic ratio of 1 homogeneous R : 2 segregating (3R:1S) : l homogeneous S. The results indicate that each of these five resistant parents has a single, …
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