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Showing 1 to 2 of 2 for “"3D-tumor models"”.

  1. Engineering Tumor-Targeting Bacteria and Characterizing Their Interactions with Tumor Cells in Therapy-Resistant Breast Cancers

    … or resistant ER+, and Luminal B tumors. For these high-risk subtypes, molecular heterogeneity undermines targeted therapies, and clinical management still relies on maximum tolerable doses of systemic chemotherapy, causing severe dose-limiting toxicities. Moreover, the dense …

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  2. Engineered microsystems and their application in the culture and characterization of three-dimensional (3D) breast tumor models

    … have been utilized for engineering the tumor extracellular matrix, but very few studies have thoroughly characterized the phenotypic changes in their cell models, which is critical for translational applications of biomaterial systems. The overall objective of these studies is to …

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