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Showing 1 to 1 of 1 for “"3BNC60"”.
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Targeting the CD4 Binding Site of HIV
… (GLVH) or mature mutated (MuVH) version of 3BNC60 was knocked into the JH4 locus in mice. 3BNC60 is a bNAb that targets the CD4 binding site (CD4bs) of HIV-1 and belongs to the IgHV1-2 class of broadly neutralizing CD4bs antibodies. In the first part of my thesis I will describe the …