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Showing 1 to 1 of 1 for “"36Cl- Flux assay"”.
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Design and Syntheses of Potential Drugs Based on GABA(A) Receptor Pharmacophores
… comparable to that of THIP, as shown by in vitro assay results. The assay data indicate that the agonism of GABA amides is tether length-dependent. Optimum agonism is achieved with a tether length of four methylenes in GABA amide dimers and in GABA amides bearing pendant amide or amino groups. We …