Global ETD Search
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Showing 1 to 5 of 5 for “"30S assembly"”.
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Study Of Protein-Rna Interactions Using Fluorescence Resonance Energy Transfer (fret) And Single-Molecule Fret
… that alter the junction dynamics affect 30S assembly. Although partially functional mutants are complemented by over-expression of S15, nonfunctional mutants are not. Comparison of the structural dynamics of these mutants and WT sequence in the presence and absence of S15 revealed …
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Synthesis, Screening and Cocrystallization of Adenosine Based Inhibitors with Methyltransferases, ErmC' and KsgA
… streptogramin B). KsgA aids in ribosome assembly, binding inactive 30S until dimethylating A1518/A1519 of 16S rRNA. Like most methyltransferases, ErmC’ and KsgA use cofactor S-adenosylmethionine (SAM) as their methyl source, which binds adjacent to their specific adenosine substrate. …
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The Genesis of Ribosome Structure: A Tale of Two Proteins
… each composed of RNA and proteins. Proper assembly of each subunit is essential to ribosome function and therefore essential to the cellular life cycle. Previous studies focused on dissecting the assembly of the small ribosomal subunit (30S subunit) from E. coli have shown that 21 proteins …
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The Genesis of Ribosome Structure: A Tale of Two Proteins
… each composed of RNA and proteins. Proper assembly of each subunit is essential to ribosome function and therefore essential to the cellular life cycle. Previous studies focused on dissecting the assembly of the small ribosomal subunit (30S subunit) from E. coli have shown that 21 proteins …
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Evolution and assembly of the ribosome
The ribosome is a large macromolecular assembly responsible for protein synthesis in all living cells. A typical bacterial ribosome consists of three ribosomal RNA (rRNA) molecules and approximately fifty ribosomal proteins (r-proteins), which are arranged into two subunits of unequal size and …