Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 70008 for “"3"”.
-
Synthese bioaktiver 3-Acyltetronsäuren und 3-Acyltetramsäuren
Ketenylidentriphenylphosphoran 21 ist ein vielseitig verwendbarer Synthesebaustein in der Organischen Chemie. 21 reagiert mit aciden Verbindungen wie Aminoestern, Hydroxyestern bzw. Thioestern unter einer Protonierungs-Additionsreaktion zu Amid-, Ester- bzw. Thioesteryliden. Letztere unterliegen …
-
Modified 3+3 Design for MTD Re-estimation
The 3+3 clinical trial design is one of the most popular dose-finding designs used in phase I oncology trials to identify the maximum tolerated dose (MTD) for new treatment regimens. While this design is widely used due to its simplicity , it has some notable limitations, including a maximum of six …
-
Protein kinases that phosphorylate 14-3-3 isoforms
14 -3 -3 is an abundant, predominantly phospho-binding protein, intimately involved in the regulation of many diverse signal transduction events including cell cycle regulation, nucleo-cytoplasmic targeting of essential transcription factors and regulation of catecholamine synthesis. The 14 -3 -3 …
-
The synthesis and reactivity of 3-amino and 3-oxycyclopentadienones
[2+2+1] iron and cobalt mediated cycloadditions have been applied towards the synthesis of 3-amino and 3-oxycyclopentadienones. These methods have provided an efficient means of generating [3.3.0], [4.3.0], and [5.3.0] bicyclic-cyclopentadienone ring systems. In an effort to probe the reactivity of …
-
Furuvellir 3, Hafnarfirði
Teikningar af húsi í hafnarfirði sem ég fékk úthlutað sem verkefni.Með fylgir skýrsla.
-
3+1 Dimensions
This Paper discusses the artwork produced for this thesis 3+1 Dimensions The paper discusses the works from an historical and theoretical perspective, focusing in particular on my influences which come from the larger scientific discipline of Quantum Mechanics. Connections are also made from the …
-
Klonering en uitdrukking van die mensgeen vir interleukin-3 (IL-3)
CLONING AND EXPRESSION OF THE HUMAN GENE FOR INTERLEUKIN-3 (IL-3) The hematopo"ietic growth factor, IL-3, is responsible for the proliferation and differentiation of pluripotent stemcells to mature effector cells in the body. For the formation of mature effector cells, other hematopo"ietic factors …
-
Die Rolle der 14-3-3-Proteine beim Vorwärtstransport von Kaliumkanälen
Kaliumkanäle, die wie andere Ionenkanäle und Membrantransportproteine ein wichtiges Bindeglied zwischen dem extrazellulären bzw. luminalen Raum und dem Zellinneren darstellen, spielen eine Rolle in diversen zellulären Prozessen wie Aufrechterhaltung des Membranpotentials, Frequenz und Verlauf von …
-
Regulation of human protein kinases and phosphatases by 14-3-3
The first part of my thesis shows that a previously-uncharacterised protein FAM122A and its paralogue FAM122C form stable stoichiometric complexes with the protein phosphatase 2A (PP2A) heterotrimer (AαB55αC). Moreover, the FAM122A–PP2A complex is active and contains methylated catalytic C subunit. …
-
Synthesis and Antiviral Evaluation of Some 3'-Carboxymethyl-3'-deoxyadenosine Derivatives
3'-Carboxymethyl-3'-deoxyadenosine derivatives were prepared from 2'-O-TBDMS-3'-deoxy-3'-[(ethoxycarbonyl)methyl]adenosine (1) via simple and efficient procedures. Conversion of 1 to 5'-azido-2'-O-TBDMS-3', 5'-dideoxy -3'-[(ethoxycarbonyl) methyl] adenosine (4) was accomplished via a novel one-pot …
-
Klagerücknahme vor Rechtshängigkeit? Aktuelle Probleme des § 269 Abs. 3 S. 3 ZPO
Die Arbeit untersucht Anwendungsbereich und Handhabung des § 269 Abs. 3 S. 3 ZPO. Daneben untersucht sie die kostenrechtlichen Implikationen und das klägergünsigste Vorgehen. Außerdem befasst sie sich mit der dogmatischen und systematischen Integrität von § 269 Abs. 3 S. 3 ZPO.
-
Regulation of Mammary Gland Development and Tumorigenesis By 14-3-3 Zeta
<p>Signaling pathways that play critical roles in organ development are often aberrantly regulated during cancer initiation and progression. 14-3-3z is overexpressed in more than 40% of breast cancers and is associated with poor patient prognosis. Therefore, the function of 14-3-3z in cancer and …
-
Expression and regulation of monocyte chemoattractant protein-3 (MCP-3) in fibrosis
Systemic sclerosis is a multisystem connective tissue disease characterised by skin thickening and widespread, but variable, visceral fibrosis. The aetiopathogenesis is likely to involve immunological activation and microvascular dysfunction leading to excessive accumulation of extracellular matrix …
-
Regulation of 3-hydroxy-3-methylglutaryl coenzyme a reductase by reversible phosphorylation
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
-
The Condensation of Grignard Reagents With 3-Pyridyl and 3-Quinolyl Ketones
Made available in DSpace on 2014-12-05T19:36:35Z (GMT). No. of bitstreams: 1 0020877.pdf: 3184477 bytes, checksum: 2352efb275bbed320909b8abe8913fe0 (MD5) Previous issue date: 1957
Page 1 of 3501