Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 1 of 1 for “"2C-like cells"”.
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CRISPR activation screening at single-cell transcriptomic resolution: discovering new regulators of zygotic genome activation
… epigenetic reprogramming processes and is likely orchestrated by the interplay of epigenetic and transcriptional regulators. In this dissertation, I develop a novel high-throughput screening method that combines pooled CRISPR activation (CRISPRa) with single-cell transcriptomics and apply …