Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 501 for “"231"”.
-
Il volto "poliedrico" dell'ente nel modello processuale ex d.lgs. n. 231/2001
… a seguito dell'entrata in vigore del d.lgs. n. 231 /2001. La normativa citata ha, infatti, introdotto una nuova ipotesi di responsabilità per la societas, la cui natura è ancora piuttosto dibattuta, e che - sebbene sia formalmente qualificata come amministrativa -cela in realtà un volto …
-
Studien zur Regulation der Clusterin-Expression in der MCF-7- und MDA-MB-231-Mamma-Karzinom-Zelllinie
… Blot analyses and immunohistochemistry in MDA-MB-231 and MCF7 breast cancer cells a) after cultivation with 17beta-estradiol (E2) and E2 in combination with different progestins (medroxyprogesterone acetate, R5020 or megestrol acetate), b) after 48 hours of treatment with different doses of TSA …
-
URSOLIC ACID INHIBITED PROLIFERATION AND INVASION OF MDA-MB-231 HUMAN BREAST CANCER CELLS VIA REGULATING CELLULAR SIGNAL TRANSDUCTION PATHWAYS
… UA inhibits proliferation and invasion of MDA-MB-231 human breast cancer cells via regulating cellular signal transduction pathways. Specific objectives are designed as: a) to investigate anti-proliferation and anti-invasion effects of UA in MDA-MB-231 human breast cancer cells; b) To determine …
-
The regulation of LIV-1 mRNA in MDA-MB-231 human breast cancer cells and its association with E-cadherin (CDH1)
… of LIV-1 and its relationship to CDH1 in MDA-MB-231 ER<sup>-</sup> breast cancer cells. Cells were treated with insulin and EGF for 24 hours and the mRNA concentrations of LIV-1 and CDH1 were analyzed by RT-PCR. EGF treatment induced LIV-1 mRNA by about 2-fold whereas insulin had minor effects. …
-
Using resonant MEMS pedestal sensors and filtering techniques to determine the growth curve of MDA-MB-231, metastatic breast cancer cells
… used to measure the mass of an individual MDA-MB-231 (metastatic breast cancer) cell. The noisy mass measurements were subjected to two different processing methods: Savitzky-Golay and Moving Average. Our main goal in performing these two techniques was to determine the most appropriate processing …
-
Induction and characterization of de novo methylation by benzo[A]pyrene in the cancer cell lines MCF-7 and MDA-MB-231
… cytosine methylation patterns. MCF-7 and MDA-MB-231 human breast cancer cells were treated for a period of sixty days with 100 nM benzo[a]pyrene. The methylation status of two genes, Ecadherin and GSTP 1 were examined using methyl-specific PCR and Southern blot analysis. After sixty days, no …
-
The effects of various combinations of different classes of anticancer drugs and tyrosine kinase inhibitors on the human MCF-7 and triple-negative MDA-MB 231 breast carcinoma cell lines
… negative breast cancer (TNBC) cell line (MDA-MB-231), with specific focus on P-gp and EGFR inhibition. Analyses of MCF-7 and MDA-MB-231 TNB carcinoma cells exposure to DOX, CDDP and EGFRi included growth and dose-response curves (cytotoxicity assays), caspase3/7 assays for apoptosis detection, …
-
Role of TRAF2/6 in tumour growth and bone metastases associated with breast cancer
… metastatic bone-tropic clone of the human MDA-MB-231-BT (MDA-231-BT) breast cancer cells when compared to parental MDA-MB-231 (MDA-231) cells. Targeted knockdown of TRAF2, but not TRAF6, in both parental MDA-231 and bone-tropic MDA-231-BT breast cancer cells by siRNAs markedly reduced cell …
-
Identification of Cell Biomechanical Signatures Using Three Dimensional Isotropic Microstructures
… normal human breast epithelial cells and MDA-MB-231 metastatic human breast cancer cells. Primary findings on the first generation of silicon substrates demonstrated a distinct adhesion and growth behavior in HS68 and MDA-MB-231 cells. MDA-MB-231 cells deformed while the fibroblasts stretched and …
-
Tyrosine Kinase Inhibitors in Triple Negative Breast Cancer
… variant of the triple negative MDA-MB-231 cell line was established (231-DasB). A dose-dependent decrease in P-Src levels in response to dasatinib was observed in MDA-MB-231 but not in 231-DasB. Proteomic analysis identified 78 significantly altered proteins. Six proteins were uniquely …
-
DNA Sequence and Haplotype Variation Analyses of Circadian Clock Genes and Their Effects on Phenotypes in the Turkey, Meleagris gallopavo
… gene were significantly associated with BW at 231 d of age, average daily gain (ADG) for 160 - 231 d, FCR for 69 - 159 d and 160 - 231 d, egg production traits, semen quality traits and plasma melatonin concentration (P " 0.05). In the turCry1 gene, haplogroups were significantly associated …
-
Characterizing the pro-inflammatory cytokine response by dendritic cells upon exposure to PrP proteins
… BMDCs, however, the recombinant MoPrP 23-231 and MoPrP 90-231 elicited TNFα and IL-12 production. These results may not be surprising since PrPSc closely resembles cellular PrPC and therefore, DCs recognized PrP in brain homogenates as self-antigens. However, MoPrP 23-231 and MoPrP 90-231 …
-
Proteins mediating somatic hypermutation and class switch recombination at the immunoglobulin locus
… expressed in activated B cells. WEHI-231 is known as an immature B cell line with no evidence for SHM or CSR. Indeed, in early freezings of the WEHI-231 line the canonical AID is absent. However, we found some variant lines that express AID. But despite the presence of AID and other …
-
Stellenwert der einzeitigen operativen Peritonitistherapie
… wurde anhand der Therapieverläufe von 231 Patienten mit diffuser Peritonitis der Stellenwert des durchgeführten einzeitigen Verfahrens im Literaturvergleich zu mehrzeitigen Verfahren analysiert. Ergebnisse: Die 231 Patienten mit diffuser Peritonitis wiesen einen durchschnittlichen …
-
Effect of uptake pathway on non-viral gene delivery in vitro and in vivo
… PEI-derivative gene delivery in HeLa and MDA-MB-231 cell cultures and xenograft tumors. First, we attached transferrin and folate ligands to PEI to direct internalization by clathrin- and caveolin-mediated mechanisms, respectively, and transfected HeLa and MDA-MB-231 cells with targeted and …
-
Targeting histone deacetylase (HDACs) enzymes with novel bisnaphthalimidopropyl derivatives (BNIPs) as alternative breast cancer therapies.
… metastatic breast cancer cell lines, MDA-MB-231 and SKBR-3. A series of novel BNIPs, bisnaphthalimidopropyl-piperidylpropane (BNIPPiProp), bisnaphthalimidopropyl- ethylenedipiperidine (BNIPPiEth) and (trans(trans))-4,4-methylenebis-cyclohexylamine (trans,trans-BNIPDaCHM) were synthesised, …
-
The role of the kisspeptin receptor, KISS1R, in breast cancer cell proliferation, invasion and migration.
… 5 of the KISS1R gene in the BT-20 and MDA-MB-231 cell lines was assessed by Sanger sequencing. The results show that KISS1R protein is expressed in all the breast cancer cell lines tested albeit at significantly different levels. The non-metastatic BT-20 cell line express a much higher level …
-
Proteomic Investigation of Endocrine Therapy Resistance in Breast Cancer Investigating the Molecular Mechanisms for SERM Resistant Cell Lines Using SILAC-Based Proteomic Approach
… (IC50) was determined for MCF7, T47D, MDA-MB-231, MDA-MB-468, MDA-MB-453, BT-20 and MCF-10A breast cell lines using four endocrine-based therapeutic agents (Tamoxifen, 4-Hydroxytamoxifen OHT, Raloxifene, Anastrozole) to select viable strains for resistance studies. MCF7 (luminal-type A) and …
-
Group-theoretical applications in a tri-local model for baryons
231 leaves, appendix
-
Investigating pathways in tumour cell migration and invasion in response to novel isoquinolinone compounds
… A5 and A3 compounds reduce adhesion of MDA-MB-231 cells to Fibronectin, Matrigel, and Type I collagen which was paralleled in A5 treated HT1080 cells on these matrix components. Compound A5 also induced 2D migration of MDA-MB-231 cells on all matrix substrates. Cell movement of MDA-MB-231 cells …
Page 1 of 26