Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"20-HETE"”.
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ELUCIDATING THE ROLE OF HET0016 IN AMELIORATING 20-HETE INDUCED OXIDATIVE STRESS AND LIVER INJURY IN B-THALASSEMIA: A NOVEL THERAPEUTIC TARGET
… model of β-thalassemia through an increase in 20-hydroxyeicosatetraenoic acid (20-HETE) activity. Aim: The aim of this study is to assess the efficacy of N-Hydroxy-N'-(4-butyl-2-methylphenyl)-formamidine (HET0016), an inhibitor of 20-HETE formation, in reducing 20-HETE-mediated oxidative stress …
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Spontaneous tone in deoxycorticosterone acetate-salt hypertensive rats
… the enzyme that breaks down hydrogen peroxide (H202), increased spontaneous tone. Taken together, these findings suggest that O2.- derived from NAD(P)H-oxidase modulates spontaneous tone primarily by scavenging NO, while H202 serves as a protective mechanism. The cyclooxygenase (COX) inhibitor, …