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Showing 1 to 3 of 3 for “"2-isopropylmalate"”.
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Genome-guided bioprospecting for novel antibiotic lead compounds.
… revealed genes encoding two core enzymes: 2-isopropylmalate synthase (2-IPMS) and acyl CoA ligase homologues. In the biosynthetic pathway, 2-IPMS catalyses the condensation of acetyl CoA with the degradation product of valine or isoleucine to form 2-IPM. 2-IPM is isomerised to 3-IPM which …
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Metabolic engineering of yeast strains for renewable biomass utilization and valuable chemical production
… microbial system is necessary. I identified 2-isopropylmalate (2-IPM), and intermediate of leucine biosynthesis, as a target chemical production in yeast. The dicarboxylic organic acids are favorable for production due to possible bio-based polymer synthesis. I observed 2-IPM accumulation by …
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Engineering diverse yeast species for optimal sugar consumption and enhanced product formation
DSpace SAF Submission Ingestion Package generated from Vireo submission #9570 on 2016-07-07 at 14:18:10