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Showing 1 to 14 of 14 for “"2-MIB"”.
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Co-processing of drugs and co-crystal formers and its effect on pharmaceutical dosage-form performance. Co-crystallization of urea/ 2-methoxybenzamide, caffeine/ malonic acid, caffeine/ oxalic acid and theophylline/ malonic acid systems: Solid-state characterization including imaging, thermal, X-ray and Raman spectroscopic techniques with subsequent evaluation of tableting behaviour
This dissertation has focused on the solid-state characterization of different co-crystal system as well as the effect of co-crystallization of these systems on pharmaceutical dosage form performance. Urea/ 2-MB, caffeine/ malonic acid, caffeine/ oxalic acid and theophylline/ malonic acid …
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Determination of Henry's Law Constants of Odorous Contaminants and Their Application to Human Perception
… (about 100 mg/L). 2-Methylisoborneol (2-MIB) is a methylated monoterpene alcohol that is produced by actinomycetes and blue-green algae and has a musty odor that is detectable at 4-10 ng/L water. Geosmin, also produced by actinomycetes and blue-green algae, has a detectable earthy odor at …
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Physical mapping of a 2-Mb region centered at D10S94, a locus very tightly linked to the multiple endocrine neoplasia type 2 gene(s)
The dominantly inherited cancer syndrome multiple endocrineneoplasia type 2A (MEN 2A) is characterized by medullary thyroid carcinoma (MTC), pheochromocytoma and parathyroid hyperplasia. The related syndrome MEN 2B comprises MTC, pheochromocytoma and mucosalneuromas. Genes responsible for these …
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Positionsklonierung Bartter-Syndrom mit Taubheit (BSND)
Das Bartter Syndrom BS ist eine autosomal-rezessiv vererbte Nierenerkrankung, die in verschiedenen Formen auftritt. Es handelt sich um eine renale Salzverlusttubulopathie, die durch Defekte in verschiedenen Kanälen bzw. Transportern, die im dicken aufsteigenden Teil der Henle-Schleife exprimiert …
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A Critical Review of Telomerase Biology and Model Systems for the Study of Telomerase
The study of telomere and telomerase biology holds substantial promise in uncovering the molecular process of aging and the treatment of cancers. Studies have shown that telomere shortening is directly linked to cellular aging and that telomerase expression is found in over 85% of human cancers, …
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Phänotyp-Genotyp Korrelation für die Autosomal-Dominante Medullary Cystic Kidney Disease auf Chromosom 1q21
Die autosomal-dominante medullary cystic kidney disease (MCKD) ist eine tubulointerstitielle Nephropathie. Die durch strukturelle Veränderungen der Nierentubuli resultierende renale Funktionsstörung führt zur Einschränkung der Konzentrierungsfähigkeit der Niere mit exzessivem Salzverlust und …
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Physikalische Kartierung der RT1-C/M-Region des Haupthistokompatibilitätskomplexes der Ratte
The rat is an important model for studying organ graft rejection and susceptibility to certain complex diseases. The MHC, the RT1 complex, plays a decisive role in controlling these traits. During this work is cloned the telomeric class I region of the RT1 complex, RT1-C/E/M, of the BN inbred rat …
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States of Allelic Imbalance on the X Chromosomes in Human Females
<p>Allelic imbalance, in which two alleles at a given locus exhibit differences in gene expression, chromatin composition and/or protein binding, is a widespread phenomenon in the human and other complex genomes. Most examples concern individual loci located more or less randomly around the genome …
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Macromolecular Reactions and Sensory Perception at the Air-Water-Human Interface
… First aim was to understand when geosmin, 2-MIB, and nonadienal become detectable, employing two-resistance mass transfer theory to determine the concentration of odorants in bathroom air. Results showed that water temperature and odorant concentration in water play an important role. Next …
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Ornithobacterium hominis isolates from a South African birth cohort
Ornithobacterium hominis is a gram-negative bacterium that colonises the infant nasopharynx. Ornithobacterium hominis 16S rRNA gene sequences have been identified in South-East Asia, Australia, Gambia and Kenya; however, this species is notably absent from cohorts based in the northern hemisphere. …
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Consumers and Their Drinking Water: Communicating Water Quality and Assessing the Reaction of Zerovalent Nanoiron (nZVI) with Saliva
… of consumers identifying the odor of orange, 2-MIB, and DMTS. All of the groups were able to identify the familiar orange odor. However, the two utility groups were much more able to identify the musty odor of 2-MIB; this may be due to the fact that the utility groups are more familiar with raw …
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Genetic Loci Contributing to Spontaneous Autoimmune Diabetes
Background and Aims: Spontaneous type 1 diabetes (T1D) in the BioBreeding (BB) rat mimics human T1D as the rats experience weight loss, polydipsia, polyuria, ketoacidosis, onset during puberty and insulin-dependency within a day after diagnosis. Because the DP rat develops T1D spontaneously, it is …
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Production of helium and neon in the lunar regolith by solar cosmic ray protons
In three sets of irradiations at Texas A and M's Variable Energy Cyclotron, stacks of thin Mg, Al, Si, Ca, Ti, and Fe foils were bombarded with 1 to 1 intermediate energy protons (15 to 45 MeV) in order to determine He, Ne, and Ar production cross sections. This energy range was selected because it …
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Behaviour of trace organics and dissolved organic matter in granular activated carbon filters for drinking water supply
Granular and biological activated carbon (GAC and BAC) filters are widely used to remove organic compounds from drinking water sources during municipal drinking water treatment. Common uses of GAC filters include removal of taste and odour (T&O) causing compounds such as geosmin and …