Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 17 of 17 for “"19s"”.
-
Sequential Actions of VCP/p97 and the Proteasome 19S Regulatory Particle in Sterol-Accelerated, ER-Associated Degradation of HMG CoA Reductase
… deficient for AAA-ATPases of the proteasome 19S regulatory particle. These findings establish sequential roles for VCP/p97 and the 19S regulatory particle in the sterol-accelerated ERAD of reductase that may be applicable to the ERAD of other substrates.
-
Spatial and temporal variability of coastal temperature and salinity in Angolan waters
… the Lobito coastal oceanographic station (12° 19S 13° 34E) mean temperature and salinity distributions and the seasonal and interannual temperature and salinity variability. The main aims of this study were thus to identify, quantify and analyze the above parameters and to establish their …
-
Identifizierung und Charakterisierung einer Protein-Protein-Interaktion beim Morbus Parkinson
… waren, bei denen Parkin mit Untereinheiten der 19S-Komplexe (Rpn10, Rpt6, Rpn1 oder Rpn2) des 26S Proteasoms interagiert. Die Untereinheit alpha4 gehört aber zu den Untereinheiten des 20S-Kernkompexes des 26S Proteasoms. Im Unterschied zu den Interaktionen mit Untereinheiten des 19S Komplexes, …
-
Transcriptional Regulatory Mechanisms of Ribosomal Protein Genes
… were performed. The results reveal that the 19S subcomplex of the 26S proteasome is recruited to the promoters of the ribosomal protein genes in a TOR (Target of Rapamycin)-dependent manner. TOR signals environmental cues and controls the expression of the ribosomal protein genes. Thus …
-
Sex-differences in proteasome-independent roles of the ubiquitin proteasome system in memory formation
… of a 20S catalytic core surrounded by two 19S regulatory caps. Phosphorylation of 19S cap regulatory subunit RPT6 at serine 120 (pRPT6-S120) has been widely implicated in controlling activity-dependent increases in proteasome activity. Interestingly, sex differences have been observed in …
-
The Expansion and Decline of The O’Donel Estate Newport, County Mayo 1785-1852
… Medlicott and Thomas John Medlicott for £33,589 19s 4d, which was equal to nineteen years and a half purchase of the rental income minus the head rent amounting to £1722 11s 3d per year. 1 The O’Donels owned land in three baronies of Mayo, the Tarmon estate in the barony of Erris, the Cong estate …
-
Doğrusal olmayan büyüme modellerinin incelenmesi ve parametre tahmini
… sıra ile, 65 494.7, 65 496.6, 1E7 281.9, 19S 664.8, 413 222.9 dur.
-
Outdoor Education and Meaningful Learning: Finding the attributes of meaningful learning experiences in an outdoor education program
… period allowed for reconstruction of a person 19s view of himself or herself and this was closely tied with feedback from others in the group. The findings of this study can give educators specific components that appear to be crucial ingredients to meaningful learning experiences.
-
An Examination of the Meaning of Family Recreational Storytelling among Parents and their Adult Children
… them to see situations from another person 19s perspective. Adult children reported positive changes in attitudes toward their parents as a direct result of family recreational storytelling. Family history stories appeared to be related to the creation of a family identity. The role and …
-
Inhibition des 26s Proteasoms : molekularer Mechanismus der Hyperthermie in Prostatakarzinomzellen?
… dieser Protease ist vermutlich Teil ihrer 19s Regulationseinheit. Hyperthermie blockiert die Expression des Androgen Rezeptors in androgenabhängigen Zellen und könnte somit den Malignisierungsprozeß eines PKs beschleunigen.
-
A Role for PI31-Mediated Proteasome Regulation in Proteostasis and Neuronal Health
… two subcomplexes: a 20S core particle (CP) and a 19S regulatory particle (RP) that caps one or both ends of the 20S proteasome. Most investigations on proteasome regulation have focused on substrate recognition, binding, deubiquitination, unfolding, and translocation. However, evidence shows that …
-
The proteasome and its ancillary proteins
… caps, with no evidence for the 26S proteasome 19S regulatory particle. There was also a low abundance complex with a smaller, less-resolved density, that could be assigned to PI31. Surprisingly, these experiments suggest a regulatory role of PI31 in the selective assembly of higher order …
-
Quality control of protein complex assembly
… required for efficient degradation of PSMC5 (a 19S proteasomal subunit) and CCT4 (a chaperonin subunit). This was unexpected because orphaned PSMC5 and CCT4 were recently shown to be multiply mono-ubiquitinated by the E3 ubiquitin ligases HERC1 and HERC2, respectively. This led to the hypothesis …
-
Polyhalite alters the uptake and partitioning of mineral nutrients in corn
… with the trade name POLY4 (0-0-14-10Ca-4Mg-19S). The granulated version of polyhalite has several unique chemical characteristics that allow for a synchronized release of each nutrient in a season-long fashion. The slow-release delivery of POLY4 is the result of the fertilizer’s physical …