Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"18F-fluoride"”.
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Molecular imaging of calcification and inflammation in aortic valve disease and atherosclerosis
… (CT) and molecular processes (PET) in vivo. The 18F-sodium fluoride (18F-fluoride) isotope has shown promise in early cardiovascular studies. The purpose of this thesis was to elucidate the mechanisms of cardiovascular 18Ffluoride uptake and define how 18F-fluoride PET/CT might play a role in the …
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Imaging of abdominal aortic aneurysm disease activity and implications for endovascular aneurysm repair
… tissue (on computed tomography) and sodium [18F]fluoride positron emission tomography, in different abdominal aortic aneurysm disease states to better understand the disease process and to assess its implications in EVAR. METHODS: First, we assessed periaortic adipose tissue attenuation in 70 …
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Novel molecular imaging of cardiovascular disease in man
… tomography-computed tomography (PET-CT), 18F-fluorodeoxyglucose and 18F-fluoride were utilised as markers of metabolic inflammation and active calcification. Cellular inflammation was assessed using ultrasmall superparamagnetic particles of iron oxide (USPIO) enhanced magnetic resonance …
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The development of a simple process for producing medicinal diagnostic 18F agents for molecular imaging using positron-emission-tomography
… (RLV) approach for the synthesis of [18F]-fluoride radiotracers for use as imaging agents in positron-emission-tomography (PET). The RLV strategy immobilises a precursor to the desired radiotracer on a solid support which is cleaved on exposure to [18F]-fluoride ion to give the …
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Novel applications of fluorine-18 labelled radiotracers in cardiovascular disease
… disease. METHODS AND RESULTS: Cardiovascular ¹⁸F-fluoride positron emission tomography-magnetic resonance imaging: a comparison study: Eighteen patients with aortic stenosis or recent myocardial infarction underwent ¹⁸F-fluoride PET/CT followed immediately by PET/MR. Valve and coronary …
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Development of Novel PET Radiotracers for Neuroinflammation and COVID-19: Targeting FPR2, I2BS and ACE2
… were developed to produce [11C]Quin C1 and [18F]Quin C1-click-F, two potential FPR2-targeting PET radioligands identified through collaboration with Imperial College London. Radiotracer [11C]Quin C1 was produced with decay-corrected radiochemical yield (d.c.RCY) (decay corrected to the start …
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Optimalisation de la radiosynthèse et production au niveau de la curie d'acides aminés aromatiques marqués au fluor-18
6-[18F]fluoro-L-dopa (FDOPA) and 2-[18F]fluoro-L-tyrosine (FTYR) are useful radiopharmaceuticals for evaluation by positron emission tomography (PET) of the dopaminergic function and oncological studies, respectively. In comparison to electrophilic synthesis, the no-carrier-added (nca) nucleophilic …
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Microfluidic modules for pre-concentration of [¹⁸F]fluoride in positron emission tomography (PET) radiotracer synthesis
… here results for on-chip pre-concentration of fluoride, together with some preliminary results on the removal of Kryptofix (K2.2.2) and the purification of fluoroethyl-dimethyl-2-hydroxy-ethylammonium (FECH) are presented. Here in, three microfluidic modules for fluoride pre-concentration are …