Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"17-beta-estradiol"”.
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Mechanisms of 17-beta-estradiol regulation of the proto-oncogene Bcl-2 in MCF-7 human breast cancer cells.
… virtually undetectable levels of p53 nor MCF-7/173L cells expressing a DNA binding domain mutant p53, showed altered E2-mediated induction of Bcl-2 mRNA or protein levels. However, MCF-7 cells expressing a truncated mutant p53 protein (Delta291) resulted in a dramatic decrease in Bcl-2 protein …
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Der Effekt von Dihydrotestosteron, 17 beta Estradiol, Genistein und Equol auf den osteoporotischen Knochen der männlichen Ratte nach Trepanation dargestellt durch das pQCT
Die Effekte von Dihydrotestosteron, 17b Estradiol, Genistein und Equol auf den osteoporotischen Knochen der männlichen Ratte nach Trepanation dargestellt durch das pQCTEinleitung: Immer mehr Männer erkranken durch das zunehmende Alter an Osteoporose. Hohe Knochenbrüchigkeit und erschwerte …
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Labeling of Proteins, Peptides, and Estrogens With Cyclopentadienyltricarbonylrhenium and Technetium
… approach, and of the compounds synthesized, ((17$\beta$-estradiol-17$\alpha$-yl)-ethynylcyclopentadienyl) tricarbonylrhenium and its 11$\beta$-chloromethyl, ethyl and methoxy derivatives are attractive candidates for imaging estrogen receptors in vivo, having relative binding affinities (RBA's) …
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The effect of gender on Helicobacter pylori and gastric cancer
… of the immune response. In the second aim, 17[beta]-estradiol prevented the formation of gastric cancer in the INSGAS mouse model, which develops gastric cancer in a male-predominant manner. Unexpectedly, this study led to the discovery that Tamoxifen may act as an agonist in this model of …
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Steroid Stimulated Protein Synthesis in Fish Cell Cultures
… cell cultures (CHSE-214) was stimulated by 17-beta-estradiol, 17-alpha-hydroxyprogesterone, and testosterone. Cells were treated for six hours with a 10-6 M concentration of steroid and radiolabelled with 35s-methionine for one or three hours. Testosterone produced the greatest response in …
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Fluorine-18-labeled estrogens, progestins and corticosteroids for receptor-based imaging of breast tumors and target areas of the brain
… (n-Bu$\sb4$N$\sp{18}$F) displacement of a 16$\beta$-trifluoromethanesulfonate (triflate) derivative of the corresponding estrone 3-triflate, and purification by HPLC. That sequence has been used to synthesize the 11$\beta$-methoxy 1 and 11$\beta$-ethyl 2 analogues of the breast tumor imaging …
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ΑΝΟΣΟΙΣΤΟΧΗΜΙΚΗ ΑΝΙΧΝΕΥΣΗ ΥΠΟΔΟΧΕΩΝ ΟΙΣΤΡΟΓΟΝΩΝ ΣΕ ΚΑΡΚΙΝΟ ΤΟΥ ΜΑΣΤΟΥ. ΣΥΓΚΡΙΤΙΚΗ ΜΕΛΕΤΗ
… BY USING AS PRIMARY ANTISERUM RABBIT ANTI-17 BETA ESTRADIOL-BSA AND WITHOUT PREVIOUS INCUBATION OF THE SECTIONS WITH EXOGENOUS ESTROGEN. ALL CASES WERE ALSO BIOCHEMICALLY TESTED FOR ER BY USING DCC METHOD. THE PRESENT IMMUNOHISTOCHEMICAL METHOD IS RELIABLE AND CAN BE EASILY PERFORMED …
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Estrogen's Effects on Oxidative Stress Levels in Glial Cells
… 10nM - 10 uM. Two endogenous human estrogens, 17 alpha-estradiol and 17 beta-estradiol, and two equine estrogens, equilin and equilenin, were utilized. Only 17 alpha-estradiol showed a statistical difference in the oxidative stress levels of astrocytes. However, the results indicate that …
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Postpartum ovarian activity and response to progestagen treatment in rustic beef cows (Spanish Retinta) underfed to simulate their typical ranging conditions
… 2nd to the 9th month postpartum and assayed for 17-[beta]-estradiol and progesterone. Intact bulls were used for breeding and estrous detection. Calves were weaned at 7-7.5 months of age. Twenty-seven cows showed estrus (on the 16-35th week postpartum) and 24 cows were confirmed pregnant (on the …
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Degradation and transport of veterinary antibiotics and estrogens in a vegetated buffer strip system
… and the estrogenic hormones estrone (E1) and 17[beta]-estradiol (E2[beta]) is important for assessing and mitigating the movement of these VAs and estrogens to surface or groundwater resources. Vegetative buffer strips (VBS) affect soil properties that enhance the removal of organic pollutants …
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Peripubertal Binge Ethanol, Age and Sex Modulate Microrna Expression in the Ventral and Dorsal Hippocampus of the Adolescent Rat
… in the ventral hippocampus dependent on age and 17β-estradiol (E<sub>2</sub>). We examine whether microRNA expression, microRNA biogenesis enzymes Drosha and Dicer, and microRNA target genes BDNF and SIRT1 are altered by peripubertal binge EtOH in the ventral and dorsal hippocampus. We also …
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Estrogen Receptor-Mediated Gene Expression in Cultured Epithelial Cells of Rat Efferent Ductules
… display PCR analysis demonstrated that 17$\beta$-estradiol altered gene expression in cultured efferent ductule cells, and this effect was reversed by treatment with ICI 182,780, a pure antiestrogen. The differentially displayed products were tested in Northern blot hybridization and …
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Tissue-Specific Mediation of Estrogen-Induced Epithelial Events by the Estrogen Receptor in Female Reproductive Tract Organs
… proliferative and differentiative effects of 17-beta estradiol (E2), is present in both stroma and epithelium of female reproductive tract organs. Although, the epithelial response to E2 has been assumed to be mediated directly through epithelial ER, indirect mediation by stromal ER may be …
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The Effects of Estrogen Receptor -Alpha, Estrogen and Phytoestrogen on Global Myocardial Ischemia -Reperfusion Injury
… a phytoestrogen-free diet and was implanted a 17 beta-estradiol capsule subcutaneously (OVX+E2 group). One group was ovariectomized and fed a diet containing 49.39 mg isoflavones/g protein (HPE group). One group was ovariectomized, fed the same diet as the HPE group and treated with ICI 182780 …
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Use of estradiol-BSA conjugates to characterize membrane estrogen binding sites in brain cells: Biochemical and physiological studies
… and sensitive radioligand binding assay using 17$\beta$-estradiol covalently linked with ($\sp{125}$I) -labeled bovine serum albumin (17$\beta$-E-6- ($\sp{125}$I) BSA conjugate), as a ligand. These membrane binding sites (dissociation constants of 3-34 nM and total binding sites of 3-40 pmol/mg …
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The effect of boron supplementation on bone mineral density and hormonal status in college female athletes
… were determined at 0, 6, and 10 months: serum 17-Beta estradiol progesterone, and testosterone, and percent body fat, and body weight. The athletes had a significantly greater V02MX (p < 0.05) than the sedentary group. There were no differences between the A and the S groups' food intake as …
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Studies of the PTEN tumour suppressor in endometrial cancer.
… reflects the menstrual cycle. The role of TGF-beta1 in PTEN expression of PTEN in human cells has been also investigated, but the results are contradictory. Compounds which stimulate up-regulation of PTEN represent potential anti-tumour therapies and therefore merit investigation. To further …
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The Interaction of Equol and Genistein on Estrogen Dependent Tumors and Bones in Ovariectomized Athymic Nude Mice
… the T47D cell proliferation similarly as 0.1 nM 17-beta-estradiol in vitro. However, 250 ppm and 750 ppm dietary equol, which gave the total plasma equol concentrations (95% CI) 2.24+/-1.0 muM and 6.84+/-2.41 muM respectively, didn't affect either the tumor growth or bone metabolism compared with …
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