Global ETD Search
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Showing 1 to 4 of 4 for “"14-3-3zeta"”.
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Developmental Deregulation and Tumorigenesis Inhibition In 14-3-3Zeta Knockout Mouse
… related death in women of the United States. 14-3-3s are a family of conserved proteins ubiquitously expressed in all eukaryotic organisms. They form complexes with hundreds of proteins by binding to specific phospho-serine/threonine containing motifs. In this way they regulate a variety of …
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Regulation of Breast Cancer Initiation and Progression By 14-3-3Zeta
<p>14-3-3ζ is a ubiquitously expressed family member of proteins that have been implicated to have oncogenic potential through its interactions and involvement in cancer initiation and progression.<strong> </strong>14-3-3ζ belongs to the highly conserved 14-3-3ζ protein family and modulates …
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Cellular mechanisms that modulate kainate receptor trafficking and assembly
… also co-precipitated with three isoforms of 14-3-3 proteins; only the KA2 and 14-3-3zeta association was correlated with higher plasma membrane expression of receptors. In addition to identifying cytoplasmic chaperone systems, we were interested in understanding the nature of a recently …
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Regulation of Mammary Gland Development and Tumorigenesis By 14-3-3 Zeta
… during cancer initiation and progression. 14-3-3z is overexpressed in more than 40% of breast cancers and is associated with poor patient prognosis. Therefore, the function of 14-3-3z in cancer and normal mammary gland development was investigated utilizing multiple <em>in vivo</em> and …