Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"129/SvJ"”.
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CD23's Role as a Negative Regulator of Allergic Disease: in vivo Effects of Murine CD23 Destabilization and Allelic Mutations
… the ADAM investigation, we discovered that the 129/SvJ inbred mouse strain carried five amino acid substitutions within its CD23 gene. The mutations resulted in reduced CD23 surface expression and hyper IgE levels in vivo. The hyper IgE phenotype was consistent with a more rapid clearance of …
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Using knockout mice to study the molecular mechanisms that shape auditory nerve responses
… sensitivity as it ages); and C57BL/6 and 129/SvJ (because they are used in "knockout" generation). Two lines with targeted deletion of inner ear genes were also studied. The cochlea in mouse responds to frequencies octaves higher than in humans or most other mammals; nevertheless, most …
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Ein Gen für ein neues Ubiquitin-konjugierendes Enzym: Genomische Organisation, Expression und Funktion
… genomischen Phagenbibliothek des Mausstammes 129/SvJ isoliert und charakterisiert. Mrhgc1 erstreckt sich mit seinen 13 Exons über ca. 11 kb des Genoms der Maus. Die zusammengesetzte cDNA-Sequenz zeigt eine 95 %ige Homologie zu der Nukleotidsequenz von HGC1. Auf Proteinebene beträgt die …
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The Impact Of Dietary Phytase Supplementation On Skeletal Biomechanics And Characteristics In Growing Swine And Mice
… (Yorkshire x Hampshire x Laundrace) and mice (129/SVJ x C57BL/6 line) fed phosphorus adequate diets. In addition, two other bone-impacting dietary supplements, inulin and strontium, were examined as well. These two additional supplements were examined with phytase because studies have suggested …
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Functional characterization of Pura in vivo and in vitro - Pura knock-out mice and Pura DNA unwinding activity
… ES cells. The Pura gene locus was isolated from 129/SvJ Mouse Genomic Library and partially sequenced. A targeting vector using positive and negative selection was generated for homologous recombination and was finally electroporated into E14 ES cells for five times. Out of 2400 ES cell clones …