Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"0304 Medicinal and Bimolecular Chemistry"”.
-
Molecular basis of Fce receptor: IgE interactions
Allergic diseases such as asthma and hay fever cause distress to numerous individuals throughout the world, sometimes with fatal consequences. Many associated costs - physical absences, psychological corollaries or medication - are borne by the community via health agencies or the government. The …
-
The effects of oligosaccharides and probiotic bacteria on the intestinal microflora and vancomycin-resistant enterococcus
… 1) to investigate the effect of bifidobacteria and oligosaccharides on their role in suppressing the growth of pathogenic bacteria in vitro, 2) to investigate the growth, viability and activity of Bifidobacterium spp. in skim milk containing prebiotics, 3) to investigate the effect of storage …
-
Synthesis of novel thyroid hormone analogues
… Reaction between diphenyliodo-2-carboxylate and a phenoxide gave lower yields and xanthone as byproduct. Using the modified Ullmann reaction 3-phenoxybenzoic acid and two thiophenoxybenzoic acids were also prepared in good yield. Transthyretin (TTR) was isolated from human plasma by column …
-
The creation and interpretation of an elemental database for Chinese traditional herbal remedies
… advances based on the study of natural products and materials are an active and fruitful area of research. For example, the discovery of drug leads from Traditional Chinese Medicine (TCM), in particular, has resulted in a number of successful therapeutic agents that are in use worldwide. However, …
-
Production of poly(adenosine diphosphate-ribose) polymerase-1: development of an efficient production and purification protocol
… a key role in maintaining the integrity of DNA and chromatin structure. As such, this enzyme is likely to provide a useful target when using a rationale drug design approach to develop pharmaceutical reagents including cancer therapeutics. A major obstacle to this work however is that our …
-
The yeast mediated synthesis of the l-ephedrine precursor, l-phenylacetylcarbinol, in an organic solvent
l-Ephedrine and d-pseudoephedrine are important pharmaceutical products commonly found in anti-asthmatic formulations, nasal decongestant mixtures and sinus preparations. d-Pseudoephedrine is the active ingredient in "Sudafed". l-Ephedrine is currently synthesised in a three step process. The first …
-
The effect of environmental temperature on exercise metabolism
… on the severity of the environmental temperature and/or the intensity of the exercise. Research examining the effect of exercise in different ambient temperatures on muscle metabolism, in particular carbohydrate metabolism, has produced conflicting results. The definitive mechanisms whereby …