Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"저산소"”.
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The Role of PKC-δ in Hypoxia-induced Cerebrovascular Endothelial cell death.
In various cell types, PKC(protein kinase C)-δ has been found to be an important mediator during hypoxia-induced cell death. However, the role of PKC-δ in cerebrovascular endothelial cells is unknown. Therefore, we investigated the role of PKC-δ during hypoxia-induced cell death using bEnd.3 cell, …
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Dichloroacetate, a inhibitor of pyruvate dehydrogenase kinase-1, attenuates hypoxia-induced resistance to 5-fluorouracil in gastric cancer cells
In this study, I investigated whether gastric cancer with hypoxia-induced resistance to 5-fluorouracil (5-FU) could be re-sensitized following treatment with low-dose dichloroacetate (DCA), an inhibitor of the glycolytic pathway. The expression profile of hypoxia-inducible factor-1α (HIF-1α) and …
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Influence of Preoperative Transcatheter Arterial Chemoembolization on Gene Expression in the HIF-1α Pathway in patients with Hepatocellular Carcinoma
Although transcatheter arterial chemoembolization (TACE) is the most common treatment option in patients with hepatocellular carcinoma (HCC), its clinical benefits remain still controversial. Since TACE induces hypoxic necrosis in tumors, hypoxia-inducible factor 1α (HIF-1α) could …
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The Effects of Onion and Yuzu Extracts against Ischemia/Hypoxia-Induced Dysfunction of Blood-Brain Barrier
This study investigated the potential beneficial effects of natural products and their major component on redistribution of ZO-1 and FoxO3a-mediated degradation of claudin-5 during ischemia/hypoxia using the mouse middle cerebral artery occlusion (MCAO) model and hypoxia model. The possible …