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Showing 1 to 3 of 3 for “"인슐린 분비"”.

  1. Genistein-Induced Potentiation Effect on Glucose-Stimulated Insulin Secretion (GSIS) in INS-1 β-cells

    Impaired secretion of insulin as well as insulin resistance is a critical characteristic of type 2 diabetes. Thus, correction of the deficient secretion of insulin as well as improvement of insulin action is an important target for prevention of overt type 2 diabetes. Sulfonylureas have been used …

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  2. Studies of TNF- α-induced -GSIS Inhibition in INS-1 β-cell

    BACKGRAUND AND AIMS: Pancreatic β-cell which produce and secrete insulin, is responsible for regulation of plasma glucose concentration. GSIS depends on coordinated glucose uptakes, oxidative metabolism nd Ca(2+)+-triggered insulin exocytosis. Imparied GSIS is a hallmark of type Ⅱ Diabetes. It has …

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  3. Role of PARK2Gene in Maintenance of Pancreatic Beta Cell Functions

    Type 2 diabetes (T2D) is characterized by decreased insulin secretion and action. Although many studies have reported the genetic loci/genes for susceptibility to T2D, the vast majority of genetic factors in T2D are still unknown. Mitophagy, a selective elimination system for impaired mitochondria, …

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