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Showing 1 to 2 of 2 for “"세포노화유도"”.

  1. Regulation of Senescence Phenotypes by TIS21 gene in Huh7 Human Liver Cancer Cells

    일반적으로 Cellular senescence란 시간이 지나면 자연적으로 세포 증식이 억제되고 세포내 항상성 유지가 어렵게 되는 것을 말한다. 이러한 cellular senescence는 tumour cell에서도 일어나는데 tumour cell에서의 senescence는 그 결과가 tumour-suppression 으로서도 작용하지만 tumour-promotion 으로서도 작용되어질 수 있다고 알려져 있다. 본 연구에서 사용한 유전자인 TIS21은 TPA에 의해 유도되어지는 21번째 sequences로서 …

    ajou Repository record for Regulation of Senescence Phenotypes by TIS21 gene in Huh7 Human Liver Cancer Cells (opens in a new tab)

  2. Induction of Cellular Induction Senescence by BTG2_(TIS21/PC3) Gene in Huh7 Hepatocellular carcinoma Cells

    TIS21^(BTG2/PC3) regulates G1-S and G2-M progressions of cell division cycle through the inhibition of G1 phase cyclin biosynthesis, and the delayed degradations of cycin B1 and cyclin A, respectively. Therefore, we earlier suggested that TIS21 might play a role as a pan-cell cycle regulator and an …

    ajou Repository record for Induction of Cellular Induction Senescence by BTG2_(TIS21/PC3) Gene in Huh7 Hepatocellular carcinoma Cells (opens in a new tab)