Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"섬유아세포"”.
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지적장애 환자에서 전장유전체분석으로 발견된 TFB2M 유전자 변이의 기능 연구
… 미치는지에 대해 연구의 초점을 맞추었다. 지적장애 환자 및 환자 아버지의 피부조직에서 섬유아세포(fibroblast)를 초대 배양(primary culture)하여 in vitro 기능 연구의 재료로 사용하였다. 이들 세포에서 TFB2M 유전자의 발현량을 비교•분석하였다. 환자와 환자 아버지 세포에서TFB2M mRNA와 TFB2M 단백질의 발현량의 유의한 차이가 없었다. TFB2M 유전자 변이가 미토콘드리아 유래의 전자전달계 관련 효소 유전자들의 전사에 미치는 영향을 조사한 결과, 아버지의 세포에 비해 환자 세포에서 이들 …
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The low-level light therapy affects human dermal fibroblast via TGF-β/smad signaling pathway: in vitro study
ABSTRACT i TABLE OF CONTENTS iii LIST OF FIGURES iv LIST OF TABLES v I. INTRODUCTION 1 II. MATERIAL AND METHODS 3 A. Isolation and culture of normal and keloid fibroblasts 3 B. Irradiation 3 C. Determination of the fluence of LLLT 3 D. Cell viability assay 5 E. Real-time polymerase chain reaction …
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The effect of low level light therapy on wound healing: in vitro study with normal and keloid fibroblast
BACKGROUND AND OBJECTIVES: Low level light therapy (LLLT) is the treatment modality which is using photobiomodulatory effect of visible to near infrared spectrum light. LLLT is used in clinically to preventing hypertrophic scar or keloid and stimulating wound healing, while the mechanism of their …
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Investigation on the Molecular Mechanism of Photorejuvenation in Photodynamic Therapy
BACKGROUND: The photoaging of the skin is characterized by wrinkles, mottled pigmentation, telangiectasia and malignancies due to the effects of long-term UV exposure. Photodynamic therapy (PDT) is a therapeutic modality for cutaneous malignant and premalignant condition. Recently, several clinical …
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Investigation on the Intracellular Sognal Transduction Mechanism of Human Dermal Fibroblasts of Photorejuvenation in Photodynamic Therapy
The clinical studies have reported over years that the photodynamic therapy (PDT) has effects on the rejuvenation of photoaged skin. However, there have been no studies on the intracellular mechanism of photorejuvenation following PDT. The purpose of this study was to investigate the effects of PDT …