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Showing 1 to 4 of 4 for “"대식세포"”.
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Regulation Mechanisms of TIM-3 expression in Jurkat T cells and HMC-1 cells
… 특이적인 세포 막 단백질로 처음 발견되었다. 이 분자는 T 세포와 비만세포 이외에도 대식세포, 수지상세포 등 면역에 관여하는 다양한 세포에서도 발현된다고 알려져 있다. 현재까지 TIM-3가 면역 반응에서 중요한 기능을 한다는 보고가 많이 되고 있는 반면 TIM-3 발현 조절 기작에 대해서는 많이 밝혀지지 않았다. 본 연구에서는 T 세포주와 비만 세포주에서 TIM-3의 발현 조절 기작을 밝히기 위해 다양한 inhibitor들을 사용한 결과 Jurkat T 세포와 인간 CD4+ T 세포에서는 MEK 경로, HMC-1 세포에서는 …
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Macrophage recruitment in DRG contributes to sensory axon regeneration after conditioning injury
The central branches of the dorsal root ganglia (DRG) sensory neurons do not spontaneously regenerate. It has been known that the sensory neurons can regenerate if their peripheral branches are severed before SCI (conditioning injury, CI). After peripheral nerve injury, macrophages accumulate in …
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Expression of Macrophage Migration Inhibitory Factor in Behçet's disease
PURPOSE: Macrophage migration inhibitory factor (MIF) is a unique protein, participating in inflammation, immune response, and cell growth. Previous reports showed that MIF-173 G>C polymorphism or the MIF-794 [CATT]5-8 polymorphism and haplotypes containing these variants were associated with an …
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Inflammatory Mediators Associated with Pre-eclampsia
PURPOSE: Pre-eclampsia, a hypertensive disorder unique in pregnancy, complicates approximately 5-7 % of pregnancies and is a leading cause of intrauterine fetal growth retardation, premature delivery, and maternal death. It is characterized by proteinuria, edema, platelet aggregation, and increased …