Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"간세포성장인자"”.
-
Green Tea Polyphenol Epigallocatechin-3-gallate Inhibits Hepatocyte Growth Factor-Induced Tumor Cell Migration and Invasion In Vitro and In Vivo
" 간세포성장인자(hepatocyte growth factor,HGF)와 그 수용체인 Met의 과 활성화는 많은 종류의 종양의 발생과 진행에 관여하는 것으로 알려져 있다. 본 연구에서는 HGF/Met 신호전달체계를 효과적으로 억제하는 물질을 찾아보고자하였고 녹차의 성분 중 생체에 영향을 주는 중요한 polyphenol인 Epigallocathechin-3-gallate(EGCG)가 HGF/Met 신호체계를 효과적으로 억제할 수 있다는 것을 발견하였다. EGCG는 HGF에 의한 Met의 활성 방식이 autocrine이든 …
-
Expression of E-cadherin and HGF in Hypopharyngeal Cancer
BACKGROUND AND OBJECTIVES: Head and neck squamous cell carcinoma (HNSCC) results from a multistep carcinogenesis process in which increasing degrees of mucosal changes and cellular atypia occur over large areas of epithelium. Hypopharyngeal squamous cell carcinoma(SCC) is well known as a aggressive …
-
The functional motifs for nucleocytoplasmic shuttling of C-terminal fragment of c-Met : A novel "pH-dependent' nuclear localization signal
The C-terminal fragment of the c-Met receptor tyrosine kinase is present in the nuclei of various cells irrespective of ligand stimulation, but neither the specific amino acid motif nor the responsible nuclear localization signal (NLS) has not been previously reported. Here, we report that two …