Global ETD Search
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Showing 1 to 3 of 3 for “"간세포"”.
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The Effect of Endocytosis of Interferon-lambda and The Genotype of IL-10RB on The Cellular Responses to Cytokines
… IL-10R2를 수용체로 이용하는 사이토카인 중 IFN-R와 IL-22R1은 간세포에서 발현되며, 바이러스 증식을 억제함이 연구 되었다. 그러나, IFN-와 IL-22의 반응성에 IL-10R2 유전자형이 미치는 영향에 대해서는 조사되지 않았다. 따라서, IL-10R2 유전자형에 따른 IFN- 또는 IL-22의 반응성에 대해 연구하고자 하였다. IFN-의 endocytosis pathway 연구에서, IFN-는 cholesterol dependent, dynamin independent pathway를 이용함을 …
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caffeine에 의한 HGF-induced G2 delay 촉진효과 확인 및 기전분석
In the present study, we explored the role of caffeine in G2 delay induced by HGF. Previously, we have shown that HGF induced transient G2 delay via ERK pathway. To address the involvement of ATM/ATR kinases in HGF-induced G2 delay, caffeine was used as an inhibitor. Interestingly, caffeine …
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The epithelial-mesenchymal transition of hepatocyte in liver cirrhosis
Liver cirrhosis is characterized by hepatic dysfunction with extensive accumulation of fibrous tissue in the liver. Even though the number of hepatocytes seems to be enough to maintain liver function, hepatic failure is one of the main causes of death in the patients with liver cirrhosis. The role …