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Showing 1 to 1 of 1 for “"β-carboline carboxamide"”.

  1. Hit to Lead Stage Optimization of Orally Efficacious β-Carboline Antimalarials

    … develop and synthesize new drugs. Tetrahydro-β-carboline acid (THβC) 1-(2,4-dichlorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-2-ium-3-carboxylate (MMV008138) has promising antimalarial properties; it was discovered by screening the Malaria Box with the so-called IPP Rescue assay. This …

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