Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"α-glucosidase inhibition"”.
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Synthesis of sulfonylthioureas as anti-diabetic drugs
… discussed the synthesis, cytotoxicity and alpha-glucosidase inhibition of sulfonamides and novel sulfonylthiourea compounds. Three series of novel sulfonylthiourea [benzamido-benzenesulfonylthiourea (28a-28d), pyrrolidino-benzenesulfonylthiourea (33a-33c) and acetamido-benzenesulfonylthiourea …
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Anti-Diabetic and Anti-Obesity Activities of Cocoa (Theobroma cacao) via Physiological Enzyme Inhibition
… and anti-obesity bioactivities, such as inhibition of certain enzymes in the body. Polyphenol profiles, protein-binding abilities, presence of compounds termed oxidative polymers, and abilities to inhibit α-glucosidase, pancreatic α-amylase, lipase, and dipeptidyl peptidase-IV (DPP4) in …
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Phytochemistry and biological studies of constituents from Breonadia Salicina (VAHL) Hepper and J. R. I. Wood
… extracts were determined using α-amylase and α-glucosidase inhibition assays. The anti-inflammatory activities of the crude extracts were assessed using the Griess assay, while the in vitro toxicology of the crude extracts was evaluated using cell toxicity, NucRed nuclei dye, MTT …
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In vitro evaluation of the enzyme inhibition and membrane permeation properties of benzophenones extracted from honeybush
… can be controlled by honeybush tea is enzyme inhibition in the gastrointestinal tract. The aim of this study was to determine the enzyme inhibition (i.e. lipase and α-glucosidase) effect of crude honeybush extracts, benzophenone rich fractions and xanthone rich fractions from Cyclopia …
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Characterization of blackcurrant berries (Ribes nigrum) and the evaluation of their bioactive compounds after ultrasound-assisted water extractions, enzymatic treatments, and fermentation
… their effect on the activities of α-amylase, α-glucosidase, DPPIV, as biochemical markers of diabetes. In addition, the antioxidant capacity was measured using 2,2- diphenyl-1-picrylhydrazyl (DPPH·), after water-based ultrasound assisted extraction, treatment with pectinase and fermentation. BC …
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Production, characterization and evaluation of anti-diabetes peptides from proteins of improved common bean (Phaseolus vulgaris L.) cultivars using bioinformatic tools, enzymatic systems, and in vitro and in vivo models
… enzyme, dipeptidyl peptidase IV, and α-glucosidase inhibition (Aim 2). Negro Otomi cultivar presented the lowest IC50 to inhibit DPP-IV (0.14±0.01 mg DW/ mL). The effect of processing was evaluated in Aim 3, where the goal was to determine the bioactive properties of the released …
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Comparison of chickpea varieties, optimization of hydrolysates production, peptide identification and evaluation of biomarkers for type 2 diabetes in the application of a value-added tortilla.
… analgesic, angiotensin I-converting enzyme inhibition, hypocholesterolemic, anticancer, and anti-inflammatory properties. On the other hand, in the U.S. diabetes mellitus (DM) affects around 10-13% of the population and it is the 7th leading cause of death. Pulses such as common bean have …
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Antioxidant and antihyperglycemic potential of soybean hydrolysates
… of peptides with potent AC as well as α-glucosidase and α-amylase inhibitory activities. Nine protein-based beverages and ten functional ingredients (I-5 to 14) were analyzed for their AC and starch-hydrolyzing enzymes inhibitory activity. Four beverages and four protein-based ingredients …
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Evaluation of the antioxidant and anti-diabesity potential of cyclopia maculata using in vitro non-cell based screening models
… potential was assessed in terms of the inhibition of the digestive enzymes, α-glucosidase and pancreatic lipase