Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 42 for “"α-Tocopherol"”.
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Lutein and α-tocopherol biodistribution in animal models
Carotenoids and vitamin E (α-Tocopherol; αT), the two most plentiful groups of lipophilic antioxidants in plants, serve important functions in the human body. The carotenoid lutein is prevalent in green leafy vegetables and is one of the most abundant carotenoids in serum and tissues. Of particular …
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The Synthesis of α-Tocopentaenol (αT5), a Fluorescent Analogue of α-Tocopherol
This thesis is focused on the investigation of synthesizing a fluorescent analogue of vitamin E, α-tocopentaenol (αT5). α-Tocopentaenol contains five conjugated double bonds across the phytyl tail, resulting in its fluorescence characteristics. Different methodologies of preparation were attempted …
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Mechanism of tocopherol transfer by human α-tocopherol transfer protein (α-hTTP)
… to describe a family of eight stereoisomers of tocopherols. Selective retention of a-tocopherol in the human circulation system is regulated by the a -Tocopherol Transfer Protein (a-TIP). Using a fluorescently labelled a-tocopherol (NBD-a-Toc) synthesized in our laboratory, a fluorescence …
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Development of Polymeric Nanoparticles Containing a Natural Antioxidant (α-Tocopherol) for the Treatment of Spinal Cord Injury
… loaded with naturally occurring antioxidant α–tocopherol (α–TP) for delivery to the injured site in SCI. Calcium alginate NP (CA–NP) and poly lactic co–glycolic acid (PLGA) NP were prepared by ionotropic gelation and solvent evaporation technique to obtain a particle size (PS) of 21.9 ± 11.19 …
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Peroxidative protection of parenteral admixture by d-α-tocopherol and its effect on oxidative status of obese cats
… PA and in obese cats given HL:LD PA. Natural d-α-tocopherol (Vital E-300) was added to HL:LD PA at seven concentrations (8, 12, 16, 24, 32, 48, or 64 IU/g of lipid). PA were exposed to fluorescent light for 24 hours at room temperature. Hydroperoxides were measured at baseline and 24 hours hang …
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Vitamin E und der vesikuläre Transport : Untersuchungen zu den genregulatorischen Funktionen von Vitamin E mittels Microarray- und real time PCR-Analysen in der Maus und funktionellen in vitro Assays in RBL-2H3 Zellen
… verlagert. Besonderes Interesse gilt dabei dem α-Tocopherol, der häufigsten Vitamin E-Form im Gewebe von Säugetieren, und seiner Rolle bei der Regulation der Genexpression. Das Ziel dieser Dissertation war die Untersuchung der genregulatorischen Funktionen von α-Tocoperol und die Identifizierung …
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Determination of tocopherol isomers and fatty acids in cottonseed oil and oil blends during accelerated storage
… the oxidative stability and the amount of tocopherol isomers in cottonseed, corn, canola, peanut and pecan oils and 50% cottonseed oil blends and also commercially available cottonseed oil containing TBHQ. The oil samples were stored at 65°C for a total of 120 days. The α and γ-tocopherol …
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The effect of feeding mixed tocopherol oil on body accumulation and immune cell functions in lactating holstein dairy cows
Non-α-tocopherol (i.e. β, γ, and δ-tocopherol) supplements are as important as α-tocopherol with regard to maintaining lactating dairy cow health. However, information on non-α-tocopherol bioaccumulation and its effects on immune cell function is not available. A series of experiments were …
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Der Metabolismus der Tocopherole und Tocotrienole
Vitamin E ist der Überbegriff für 4 Tocopherole (α, β, γ und δ) sowie 4 Tocotrienole (α, β, γ und δ), die als gemeinsames Merkmal ein Chromanolringsystem sowie eine gesättigte (Tocopherole) bzw. ungesättigte (Tocotrienole) Seitenkette aufweisen. Neben ihrer antioxidativen Wirkung (Schutz von …
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Impact of body weight gain on liver metabolism and selected fat-soluble vitamins in ponies and horses
… (z.B. Vitamin A - Retinol und Vitamin E - α-Tocopherol) in der humanen Adipositas Forschung. Viele Studien konnten ein Absinken von Vitamin A und Vitamin E in fettleibigen Menschen feststellen. Ziele Die vorliegende Studie sollte den Einfluss von zunehmendem Körpergewicht (KG) in Ponys und …
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Probes of tocopherol biochemistry: fluorophores, imaging agents, and fake antioxidants
… result of a selection process mediated by the α-tocopherol transfer protein (α-TTP), α-tocopherol is the only form of vitamin E retained in the body. This chaperon protein has been well studied because of its role in vitamin E transport. Furthermore, malfunctions of α-TTP cause vitamin E …
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The Dose Response Effect of Almonds on Serum Vitamin E, Plasma Lipid Fractions and Erythrocyte Phospholipids
… were taken after each 4 week period. Serum α-tocopherol concentrations increased in subjects consuming the low and high almond group, and a dose response effect was found. A 1 % increase of energy from almonds resulted in a 0.5μmol/L increase in α-tocopherol in plasma and a 0.005μmol/L …
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Comparative Impacts of Irradiation on Antioxidant Compounds of Scalded and Non-scalded Skin of Granny Smith Apples
… antioxidants – ascorbic acid, total phenolics, α-tocopherol, carotenoids, chlorophyll, and campesterol – in scalded and non-scalded apple peel tissue. Apples were treated with 0.2-0.77 kGy and stored at 0-1 °C. Irradiation at the applied doses increased scald incidence, suggesting that disruption …
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Biophysical Insights into Lipid Oxidation Effects on Membrane Self-Organization and Enzymatic Catalysis Under Extreme Conditions
… the protective role of antioxidants mainly α-tocopherol (Vitamin E) in mitigating lipid peroxidation-induced damage, as evidenced by a reduction in absorbance in the presence of α-tocopherol, observed through TBARS assay. By integrating these results with the observations from the Langmuir …
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When Lipids Meet Proteins
… Darauf aufbauend wurde die Zugabe von α-Tocopherol als antioxidative Maßnahme untersucht. Die Bildung sekundärer Lipidoxidationsprodukte wurde begrenzt, während die Bildung von Hydroperoxiden und Lipidradikale nicht beeinflusst wurde. Dennoch minderte α-Tocopherol die Proteinoxidation und …
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Studies of dietary nitrate induced nitrosative stress in the upper gastrointestinal tract
… further to include the lipid antioxidants, α-tocopherol, β-carotene and BHT. All three of these antioxidants are effective in inhibiting nitrosative stress within the lipid phase. The concentration of α-tocopherol required to inhibit nitrosation is less than would be expected from the reaction …
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Effects of endocrine modifiers on growth, carcass characteristics, and blood and tissue metabolites of finishing beef cattle
… negative correlation between liver retinol and α-tocopherol was observed, which may have potential health implications. Results suggest that vitamin A supplementation up to twice the NRC-suggested concentration has little effect on performance, marbling, or lipogenic enzyme activity in yearling …
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Species-specific Myoglobin Oxidation
… microsome model study found that elevated α-tocopherol concentration enhanced lipid and Mb redox stability relative to controls (p<0.05). HNE-treated ovine Mb caused greater lipid oxidation compared to control ovine Mb in control microsomes (P<0.05).</p>
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Tocopherol content of soybean lines with mid-oleate and 1%-linolenate
… Merr.] oil is an important commercial source of tocopherol (Vitamin E). Some genetic modifications of the fatty ester composition of soybean oil have resulted in changes in the content of total tocopherol and its components. The objective of this study was to compare the tocopherol content of 20 …
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Effect of dietary fats and antioxidants on the frozen storage life of cooked pork products
… mg vitamin E per kilogram of feed increased α-tocopherol levels by 3 fold in bacon fat and by 2 fold in bacon loin muscle compared to bacon prepared from pigs fed a basal level of vitamin E (10 mg vitamin E per kilogram of feed). Bacon processed with a combination of liquid and wood smoke …
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