Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"α-Bungarotoxin"”.
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Study of biological phenomena implicated in neuromuscular ageing
… of whether it was achieved with muscle (α-Bungarotoxin), nerve (α-Latrotoxin) targeted neurotoxins or an endogenous pruning cue (SPARC), synaptic inactivity increased mitochondrial and cytosolic ROS in vivo. In addition, selectively inducing mitochondrial ROS—using mitochondria-targeted …
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Functional characterisation of aphid, Myzus persicae, nicotinic acetylcholine receptors and identification of a novel biogenic amine-gated ion channel from the honeybee, Apis mellifera
… any chaperones. This was sensitive to 0.1 μM α-bungarotoxin and responded to both acetylcholine and choline but with low affinity, as shown by EC50 values in the millimolar range (2.65 mM and 9.07 mM respectively). Further testing revealed that the α5 nAChR responded to dopamine (EC50 3.37 μM), …
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The effect of dietary neonicotinoid supplementation on innate and adaptive immune responses to porcine reproductive and respiratory syndrome virus
… as nicotine analogues neonicotinoids signal to α-bungarotoxin (α-BT) sensitive insect nicotinic acetylcholine receptors (nAChR), which are expressed throughout the insect nervous system. The predominant nAChR in the mammalian brain is the α4β2 subunit that is resistant to α-BT but the α7nAChR, …
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The Characterisation Of Bee Nicotinic Acetylcholine Receptors
… demonstrate that this construct possesses an α-bungarotoxin binding site, and is sensitive to the insecticide spinosad. This novel approach of using the NACHO chaperone to express homomeric insect α6 subunits will allow for the pharmacology of the receptor and its splice and edit variances to be …