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Showing 1 to 20 of 41 for “"α-1"”.
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Cloning and Sequencing of Bovine Na+/K= Atpase α-1 Sub-Unit
<p>The major focus of this project was cloning and sequencing the α-1 sub-unit of Na+/K+-ATase gene in bovine corneal endothelium. The Na+/K+-ATase, also called the Na+ pump, is a crucial transmembrane protein. By transporting water and ions from and through the cornea into the aqueous humor, it is …
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The Macdonald group
Given α ∈ Z, the Macdonald group G(α) is defined by G(α) = ⟨ A,B | A[A,B] = Aα, B[B,A] = Bα ⟩. It is known that G(α) is finite if and only if α ̸= 1, in which case the prime factors of |G(α)| are those of α − 1. It is also known that G(α) is nilpotent in certain cases. We show that G(α) is always …
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Biochemical and molecular characterisation of cell wall glycosyltransferases in Mycobacterium tuberculosis
The human pathogen and aetiological agent of tuberculosis, Mycobacterium tuberculosis has a cell wall architecture similar to the non-pathogenic bacterium Corynebacterium glutamicum. The availability of their genome sequences has enabled the utilisation of C. glutamicum as a model for the …
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Simulations of carbohydrate conformational dynamics and thermodynamics
In this thesis, free energy calculations are employed to establish the conformation freedom of selected carbohydrates. The focus is on the biologically important (1-4)-linked glucans, although the α(1-1) α and α(1-6) linkages are also investigated. Two principal types of potential of mean force …
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Stratégie pour l’analyse qualitative et quantitative de sirops de céréales enrichis par voie enzymatique en isomaltooligosaccharides
Les Isomaltooligosaccharides (IMO) sont constitués de monomères de glucose liés par au moins une liaison α-1-6 (IMO classique), ou dans une moindre proportion α -1-3 (famille nigero-) ou α -1-2 (famille koji-). Ils sont produits par voie enzymatique à partir d’amidon de céréales hydrolysé. Un …
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Involutory matrices, modulo m
Given the prime power factorization of a positive integer m, a method for calculating the number of all distinct n x n - involutory matrices (mod m) is derived. This is done by first developing a method for the construction and enumeration of involutory matrices (mod P<sup>α</sup>), without …
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Exploring the effect of alpha2 receptor on brain 5-HT via a mechanism-based pharmacodynamic model
Purpose: 5-hydroxytryptamine (5-HT) is an important neurotransmitter in depression. It is believed that α 1 and α 2 adrenoceptors mediate the 5-HT level in the brain. The mechanism is complex and not well explored. Especially in different combination treatments, the receptor systems may show varied …
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Developing analytical tools for saccharides in condensed phases
Carbohydrates are conformationally very complex molecules. It is this complexity that lies at the basis of the important roles that these molecules play in many biochemical and biomaterial systems. Moreover, the unusual response of these macromolecules to their environment allow them to play these …
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Heat trace and heat content asymptotics for Schrodinger Operators of stable processes/fractional Laplacians
<p>Let <em>V</em> be a bounded and integrable potential over <strong>R</strong><em><sup>d</sup></em> and 0 < α ≤ 2. We show the existence of an asymptotic expansion by means of Fourier Transform techniques and probabilistic methods for the following quantities [special characters omitted] and …
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Molecular and biochemical characterisation of novel glycosyltransferases in Mycobacterium tuberculosis
The cell wall mycolyl-arabinogalactan-peptidoglycan complex is essential in mycobacterial species, such as Mycobacterium tuberculosis and is the target of several antitubercular drugs. Arabinofuranosyltransferase enzymes, such as EmbA, EmbB, and AftA, play pivotal roles in the biosynthesis of …
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Une classe d'intervalles bayésiens pour des espaces de paramètres restreints
Ce mémoire traite d'une méthode bayésienne, analysée par Marchand et Strawderman (2013), pour la construction d'intervalles bayésiens pour des modèles de densités continues avec contrainte sur l'espace des paramètres Θ. Notamment, on obtiendra une classe d'intervalles bayésiens Iπ0,α(.), associés à …
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Logaritminės eilės begalinio indekso nehomogeninis kraštinis Rymano uždavinys sričiai, apribotai begaliniu Dini – Lipšico kontūru /
In this work is formulated and studied boundary Riemann problem of logarithmic order α≥1 for the space bounded by the infinite Dini – Lipschitz contour. In this paper is used asymptotics of Cauchy type integrals with a logarithmic density. Basically differ functions Фα(z) and Фα*(z). In the first …
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Transition from integrable to chaotic domain in spectra of spin chains
In this thesis we present an approach, similar to random matrix ensembles, in order to study the integrable-chaotic transition in the Heisenberg spin model. We consider three ways to break the integrability: presence on an external field on a single spin, coupling of an external random field with …
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Pengaruh infusa daun murbei (Morus alba L.) terhadap gambaran histologi dan berat testis tikus putih (Rattus norvegicus) diabetes mellitus kronik
INDONESIA: Daun murbei (Morus alba L.) merupakan salah satu tanaman tradisional yang mengandung senyawa antihiperglikemik dan antioksidan. Senyawa ini diketahui mampu menurunkan kadar glukosa darah yang tinggi dan memperbaiki kerusakan organ akibat peningkatan radikal bebas karena kondisi …
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Exploration of Small Peptide Binding Interactions with Inorganic Surfaces Across Timescales
Peptide adhesion presents a novel method of binding surfaces which could not otherwise be permanently bound through conventional methods. Two such surfaces of practical interest are titanium dioxide (the surface of osseous implants) and hydroxyapatite (the primary mineral component of bone). The …
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Nonexistence of Solutions to Certain Families of Diophantine Equations
<p>In this work, I examine specific families of Diophantine equations and prove that they have no solutions in positive integers. The proofs use a combination of classical elementary arguments and powerful tools such as Diophantine approximations, Lehmer numbers, the modular approach, and earlier …
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Pengaruh pemberian ekstrak etanol daun kelor (Moringa oleifera L) terhadap kadar Malondialdehide (MDA) dan kualitas spermatozoa epididimis mencit (Mus musculus L) yang dipapar timbal (Pb) asetat
INDONESIA: Timbal (Pb) merupakan zat aktif yang dapat memicu adanya radikal bebas dan dapat menimbulkan kerusakan pada sel. Adanya radikal bebas tersebut dapat dinetralisir dengan antioksidan. Salah satu tanaman yang mengandung antioksidan adalah kelor (Moringa oleifera L). Penelitian ini bertujuan …
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Pengaruh ekstrak etanol daun sirsak (Annona muricata L.) terhadap kadar enzim transaminase (SGPT dan SGOT) pada mencit (Mus musculus) yang diinduksi dengan 7,12- dimetilbenz(α) antrasen (DMBA) secara in vivo
INDONESIA: SGPT dan SGOT merupakan enzim yang digunakan sebagai indikator kerusakan hati. Hati berperan penting dalam detoksifikasi bahan toksik, salah satunya adalah DMBA. Daun sirsak mengandung senyawa antioksidan yang dapat menurunkan kadar enzim SGPT dan SGOT. Oleh karena itu, penelitian ini …
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Pengaruh ekstrak air daun katu (Sauropus androgynus (L.) Merr) terhadap panjang fase diestrus dan proliferasi epitel vagina mencit (Mus musculus L.) betina premenopause
INDONESIA: Fase premenopause merupakan awal dimulainya fase klimakterik. Fase ini dimulai pada usia 40 tahun dan ditandai dengan siklus haid yang tidak teratur, Perdarahan haid yang memanjang, jumlah darah haid yang relatif banyak, dan kadang-kadang disertai nyeri haid (dismenorea). Perubahan …
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Synthetic efforts towards the total synthesis of the Nucleoside Antibiotic, (+)-Amicetin
(+)-Amicetin is a hexopyranosyl cytosine, a relatively unexplored class of RNA-binding natural products, which are a sub-group of peptidyl transferase antibiotics. As a peptidyl transferase antibiotic, (+)-Amicetin acts as a universal antibiotic, however it has been shown to be particularly …
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