Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"ß-Lactam"”.
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THE ROLE OF BACTERIA AND ß-LACTAM ANTIBIOTICS IN CANDIDA ALBICANS INFECTION
… albicans hyphal growth. Here, we report that β-lactam antibiotics cause bacteria to release large quantities of hyphal-inducing PGN subunits into the environment, including culture media and the GI tract of mice. Of high importance, massive hyphal growth in the GI tract of treated mice due to …
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The Influence of ampC Expression and Penicillin Binding Protein Binding on the Variation of ß-lactam Induction Potential in Three Genera of Enterobacteriaceae
… organisms encode inducible, chromosomal AmpC ß-lactamases which can cause, if overproduced, resistance to all ß-lactams except the fourth generation cephalosporins and the carbapenems. The interaction of ß-lactams with penicillin binding proteins (PBPs) disrupts cell wall synthesis and in the …
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Genotyping antibiotic resistance properties of escherichia coli and campylobacter jejuni associated with diarrhoea in young children in the Vhembe District
… 11% (2/18) having fluoroquinolone (gyrA) and ß-lactam (blaCTX-M) resistance mechanisms, respectively. Five percent (1/18) of the samples carried both gyrA and blaCTX-M genes. The prevalence of Campylobacter in diarrhoeal stools was 13.8% and gyrA gene was partially detected. Conclusion: Children …
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Escherichia coli infection: mechanisms and rapid detection of resistance to the association of ß-lactams with ß-lactamase inhibitors, and impact of the Sars-Cov-2 pandemic on the morbidity and mortality of intra-abdominal infection
… MIC was tested using broth microdilution, and β-lactamase activity was determined in these isolates. Whole-genome sequencing (WGS) was performed to decipher the role of blaTEM and other genes associated with P/T-R. Changes in the outer membrane protein (OMP) profile were analysed using SDS-PAGE, …
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Abundance of Antibiotic Resistance Genes in Feces Following Prophylactic and Therapeutic Intramammary Antibiotic Infusion in Dairy Cattle
… genes ampC and blaCMY-2 encode resistance to ß-lactam antibiotics, ermB to macrolides, sul1 to sulfonamides, tetO and tetW to tetracyclines, and int1 a class-1 integrase gene that facilitates horizontal transfer of ARGs across bacteria. The 16S rRNA gene was used as a representation of bacterial …
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Modellkomplexe für zinkhaltige Hydrolasen mit Schwerpunkt auf der ß-Lactamase
… (TpZnOH) gegenüber ß-Lactamen und das Koordinationsverhalten von TpZn-ß-Aminosäurekomplexe im Hinblick auf biologisch relevante Zwischenstufen im Katalyseprozess der ß-Lactamase untersucht. <br>Die Reaktionen von TpZnOH mit ß-Aminosäuren führten zu …
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Molecular Characterization of Fluoroquinolone Resistance in Streptococcus pneumoniae
… S. pneumoniae strains with resistance to the ß-lactam and macrolide antibiotics has complicated the treatment of pneumococcal infections and created a need for new agents. Recently developed compounds within the fluoroquinolone group of antimicrobials have shown potential as anti-pneumococcal …