Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"[RNQ+]"”.
-
Structural Elucidation of [RNQ+] prions Transmissible Infectivity
… of the colorimetric assay of the yeast prions [RNQ+] and [PSI+]. These prions result from the aggregation of the proteins Rnq1 and Sup35, respectively. Changes in phenotype allows for the investigation of the structure and toxicity of yeast fibrils formed in vivo, while correlating them to what …
-
Mechanism of yeast prion portein aggregation and strain formation
… taken advantage of the yeast prions [PSI+] and [RNQ+] and their protein determinants Sup35p and Rnq1p, respectively. Using a Sup35-PrP chimera, I have investigated the effect of the disease associated oligopeptide repeat domain: ORD) expansions of PrP, on prion propagation and amyloid fiber …
-
Yeast Prion Variants as Models of the Phenotypic and Pathological Consequences of Amyloid Polymorphism
… to prion variants of another prion, [<italic>RNQ</italic>+]. I found a surprising diversity in the sequence elements that are required to maintain different [<italic>RNQ</italic>+] variants. Interestingly, I also found evidence to suggest that the prion conformation dictates the availability …