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Showing 1 to 3 of 3 for “"; ATPase Assays"”.

  1. Synthesis and Structure-Activity Relationship Studies of 3-(N-Butylethanimidoyl)-4-hydroxy-2H-chromen-2-one (BHC) Analogues for Myosin II Inhibition

    … activity of the analogues determined through ATPase assays found the trend that both longer linear alkyl and methyl-aromatic imino tails are favored. The lead analogues tested containing a hexyl and a benzyl imino tail have a IC50 values of 1.2 ± 1.0 µM and 0.8 ± 0.2 µM, respectively, to …

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