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Showing 1 to 20 of 99 for “"(2R"”.
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All-optical 2r regenerator based on self-phase modulation
… the achievable transmission distance. Optical 2R regenerators provide an effective way of coping with transmission impairments by restoring the quality of optical signals through re-amplification and reshaping (2Rs), thereby enabling reliable transmission over long distances. In this work, …
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Analysis of R-2R digital-to-analog converter with equal current switching
Analysis and performance tradeoffs of an R-2R digital-to-analog converter with equal current switching are presented. It is shown that for such architecture, the active area of the DAC grows as the resolution increases due to higher matching requirement needed. A fully binary-weighted DAC suffers …
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Neue Normwerte für ACE, sIL-2R, Lysozym und IL-8 in der Sarkoidose-Diagnostik
… Arbeit war, neue Normwerte für ACE, sIL-2R, Lysozym und IL-8 in der Sarkoidose-Diagnostik zu liefern. Bevorzugt sollten mittels ROC-Analysen Cut-off-Werte erstellt werden. METHODIK: Bei 66 Sarkoidosepatienten und 46 Patienten mit fibrosierender interstiteller Lungenerkrankung und einer …
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Ex-Chiral-Pool-Synthese von 5-Aminopiperidylessigsäuren über eine Tandem-Wittig-1,3-dipolare Cycloaddition
… zu den trans-konfigurierten Piperidylacetaten 2R-78 etablieren. Das andere Diastereomer 2S-78 sollte nach Stickstoffextrusion aus 76 durch diastereoselektive Hydrierung des vinylogen Urethans 80 erhalten werden. Überraschenderweise entstand auch hier 2R-78 als Hauptprodukt. 2S-78 konnte nur als …
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Development of new GABA uptake inhibitors derived from proline or from pyrrolidin-2-yl acetic acid
… which the four key intermediates (2S,4R)-38, (2R,4R)-38, (2S,4R)-86 and (2R,4R)-64 were synthesized. The known compounds (2S,4R)-38 and (2R,4R)-38 were prepared from (2S,4R)-25 according to literature procedures. N-protection of (2S,4R)-25 with Cbz group gave (2S,4R)-58 (90% yield). After a …
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Investigation into the Utility of the MSC ADAMS Dynamic Software for SimulatingRobots and Mechanisms
A Slider-Crank mechanism, a 4-bar mechanism, a 2R planar serial robot and a Stewart-Gough parallel manipulator are modeled and simulated in MSC ADAMS/View. Forward dynamics simulation is done on the Stewart-Gough parallel manipulator; Inverse dynamics simulation is done on Slider-Crank mechanism, …
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In Vitro Evaluation of Cancer Patient Immune Responses Following Infusion of Radiolabeled Murine Monoclonal Antibody
… sensitization. Interleukin-2 receptors (IL-2R) are expressed on the lymphocyte cell surface and released into serum soon after immune activation has begun. Another early sign of immune activation is lymphocyte proliferation. The detection of IL-2R production or increased lymphoproliferation …
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Total synthesis of N-(benzyloxycarbonyl)didemnin A
… two key fragments, (Boc-(3S,4R,5S)-Ist(TBDMS)-(2R,S;4S)-Hip-Leu-Pro-OH (Fragment I)) and (Z- scD-MeLeu-Thr(H-Me$\sb2$Tyr)-OTMSe) (Fragment II). Fragment I was synthesized, in turn, from Boc-(3S,4R,5S)-Ist(TBDMS)-OH, Bn-(2R,S;4S)-Hip-OH, Boc- scL-Leu-OH and H- scL-Pro-OMe by stepwise elongation …
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Il-2 Regulation of Il-24 Expression Leads to Growth Suppression of Melanoma Cells
… cells. These cells were found to contain IL-2R beta and gamma message by RT-PCR and also expressed higher levels of IL-24 when treated with IL-15, which shares the IL-2R beta chain. Thus we propose that IL-2 is signaling through IL-2R beta on some melanoma cells to upregulate IL-24 protein …
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Syntheses, bioactivities and conformations of peptidomimetics containing 2,3-methanoamino acids
… namely F$\{$2S,3R-cyclo-M$\}$RF-NH$\sb2$, F$\{$2R,3S-cyclo-M$\}$RF-NH$\sb2$, F$\{$2S,3S-cyclo-M$\}$RF-NH$\sb2$ and F$\{$2R,3R-cyclo-M$\}$RF-NH$\sb2$. A peptidomimetic containing two 2,3-methanoamino acids substituted in the 2 and 4 positions (ie …
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The Design and Synthesis of Novel Chiral Z-Nitrones with Applications Towards the Syntheses of Enantiomerically Pure 4-Hydroxy Amino Acids
… 4-hydroxy amino acids after several steps. (2R,4R) 4-hydroxyl-4-methylglutamic acid and (2R,4R) Monatin were both synthesized in high purity from corresponding olefins and the chiral carboisopropoxynitrone. Furthermore, the (2S,4S) enantiomers of both amino acids could be synthesized via …
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Comparative genomics of chromosomal rearrangements in malaria mosquitoes
… of repetitive elements. Among the autosomes, 2R evolved faster than other autosomes. The slowly evolved autosomes have more M/SARs than rapidly evolving arms. Breakpoint regions are enriched with repetitive elements. The study revealed that fixed inversions are distributed nonrandomly and …
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Structural and synthetic studies of bioactive natural products
… dehydroiso-α-Iapachone [2.10], (2R)-5,6- dimethoxydehydroiso-α-Iapachone [2.11], (2R)-5-methoxy dehydroiso-alapachone [2.12], 5-hydroxy-2-(1'-hydroxyethyl)naphtho[2,3-b ]furan-4,9-dione [2.13], 2-(1 '-hydroxyethyl)naphtho[2,3-b ]furan-4,9-dione [2.14]' 2-isopropenylnaphtho[ 2,3-b …
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The stereoselective synthesis of iodinated analogues of reboxetine: new imaging agents for the noradrenaline transporter
… transporter. Of most interest was the (2R,3S)-stereoisomer, which was identified as being as potent as the more studied (2S,3S)-stereoisomer. Therefore, a new series of iodoanalogues based on the (2R,3S)-stereochemical scaffold were synthesised and tested for their affinity with the …
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Vertical axis wind turbine with continuous blade angle adjustment
… theoretical maximum power coefficient of CP = b 2r+b, neglecting wind flow interference by upwind blades. This theoretical power coefficient is generally greater than the efficiency of a typical Savonius wind turbine (CP ~~ 0.15), and it reaches CP = 0.5 at the limiting blade width, b = 2r. The …
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Isolation and structure determination of the metabolites from Pseudomonas putida 39D: oxidation of di-substituted aromatics
… has been determined as cis-ααα-trifluoromethyl 2R, 3S-dihydroxy-5-bromo-4,6-cyclohexadiene 2. The absolute stereochemistry was discovered by comparison of the products from the convergent synthetic pathway of 2 and the known diol metabolite from α,α,α-trifluorotoluene, 4.
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Structural characterisation and absolute stereochemistry of some degraded carotenoids from New Zealand honeys
… shown to have the absolute configurations 1'R,2R,4R,5S,5'S, 1'R,2R,4S,5S,5'S and 1'R,2R,4R,5R,5'S, respectively. The absolute configurations of kamahines A-C were consistent with an abscisic acid precursor.
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Advanced optical techniques for high capacity transmission
… transmission systems for noise suppression and 2R regeneration. Their results show that for 2R regeneration, NOLM does improve system performance, while NILM degrades system performance due to its sensitivity to the input pulse width, and the NALM built is unstable and therefore affects system …
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ΣΥΝΘΕΣΗ ΦΑΣΜΑΤΟΣΚΟΠΙΚΗ ΚΑΙ ΚΒΑΝΤΟΧΗΜΙΚΗ ΜΕΛΕΤΗ ΣΥΜΠΥΚΝΩΜΕΝΩΝ (Β) ΚΙΝΟΞΑΛΙΝΙΚΩΝ ΣΥΣΤΗΜΑΤΩΝ ΚΑΙ ΠΑΡΑΓΩΓΩΝ ΤΟΥΣ
… AND QUINOXALINES. RELATION BETWEEN THE E1/2R AND ELUMO. SUPERDELOCALIZABILITY AND ENERGIES OF FMO WERE STUDIED.
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Rhodium-catalyzed Asymmetric Carbon-Carbon Bond Formation Leading to the Development of Rhodium/Palladium Multi-metal Catalysis
… multicomponent reactions (MC)2R. The development of a highly compatible rhodium/palladium catalyst system allowed the incorporation of a third catalyst, copper, achieving a three-component one-pot reaction. Current work on the development of the use of other metal combinations …
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