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Yale University

Influence Of Previous Cesarean Section On Clinical Outcome Of Medication Abortion

Abstract

dc:description.abstract

<p>A retrospective chart review was conducted to assess for a relationship between previous Cesarean section delivery and failure of subsequent medication abortion. Several studies have shown a positive relationship between parity and failure of subsequent medication abortion; however, these studies did not isolate method of delivery (Cotte, Monniez, and Norel 2008; Ashok, Templeton, Wagaarachchi, & Flett, 2002; Niinimäki, Martikainen, and Talvensaari-Mattila, 2004; Bartley, Tong, Everington, & Baird, 2000). The sample was 196 women who underwent medication abortion and returned for a two week follow-up appointment at an urban women's health clinic during 2005-2010. The protocol for medication abortion was 200mg Mifepristone orally followed by 400mcg of misoprostol vaginally or buccally administered 12-24 hours later. Failure was defined as positive pregnancy test at follow-up. Demographic and outcome data was collected from patient self-report pre-procedure intake and follow-up questionnaire forms. Parity regardless of delivery type increased the risk of failure (p=0.0422) but previous Cesarean section did not (p = 0.6141). Duration of cramps experienced after Misoprostol insertion were negatively correlated with age (r = -0.25448). A positive correlation was found between longer cramp duration and smoking status. Future studies may benefit from a focus on other outcome measures--such as onset and duration of cramping or bleeding--rather than simply procedure failure or success, and a larger prospective study with formal clinician-guided measure is recommended.</p>

Degree

thesis:*
Name thesis:degree_name
Master of Science in Nursing (MSN)
Level thesis:degree_level
Open Access Thesis
Discipline thesis:degree_discipline
Yale University School of Nursing
Year
2012

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Pellegrino, Lauren
Contributors dc:contributor
  • Ivy M. Alexander

Subjects

dc:subject × 1

Identifiers

dc:identifier.*
Repository record dc:identifier
https://elischolar.library.yale.edu/ysndt/1007
OAI identifier oai:identifier
oai:elischolar.library.yale.edu:ysndt-1006

Chain of custody

source
Harvested from
Yale University
Base URL
elischolar.library.yale.edu/do/oai/
Last updated
2026-07-24
Source record
OAI-PMH GetRecord
citation

Pellegrino, Lauren. Influence Of Previous Cesarean Section On Clinical Outcome Of Medication Abortion. Open Access Thesis thesis, 2012. https://elischolar.library.yale.edu/ysndt/1007