Effect of increased energy in a restricted diet on bone mineral composition and breaking load of young rat tibias

Osteoporosis is a major health problem in the United States and those that are on energy restricted diets such as anorectic subjects. Thirty Wistar strain, young male rats were fed diets with varying quantities of fat for a period of four weeks (energy intake 67--75% of requirement). The rat tibias' physical properties were measured. Bone mineral composition testing was conducted for calcium, magnesium, and phosphorus, on the tibia shaft. There were no significant differences among the parameters of length, diameter, volume, density, bone bending (elasticity), fracture load, and minerals between experimental diets. There was a negative association between bending and bone density (r - 0.48, p < 0.01). Density was also positively associated with calcium, magnesium, and phosphorus in the tibia shaft (r 0.83, 0.87, 0.93, respectively, p < 0.01) per unit volume (p < 0.01). Further studies on energy supplementation along with calcium and vitamin D under energy restricted conditions are suggested.

Name thesis:degree_name

MS

Level thesis:degree_level

Thesis

Discipline thesis:degree_discipline

Human Nutrition and Foods

Year dc:date.available

2002

Author dc:creator

• Romanchak, Marcia Ann

Contributors dc:contributor

• M. Z. A. Nomani.

• Nutrition

Identifier

https://researchrepository.wvu.edu/etd/1495

OAI identifier oai:identifier

oai:researchrepository.wvu.edu:etd-2498