SOX7 is downregulated and functions as a tumor suppressive transcription factor in breast cancer

Second only to lung cancer, breast cancer is the leading cause of cancer-related deaths in American women. Breast cancer is a heterogeneous set of diseases characterized by aberrant genetic and epigenetic states, often leading to the ablation of tumor suppressors. Loss of tumor suppressor function has been established as a driver of disease progression in breast cancer patients. Thus, understanding the deregulation of tumor suppressor activity may lead to the identification of potential therapeutic targets whose inhibition can restore tumor suppressor function and, consequently, an anti-proliferative cellular state.

Grantor dc:publisher

Wake Forest University

Year dc:date.issued

2014

Author dc:creator

• Stovall, Daniel B.

• breast cancer

Language dc:language.iso

en

Handle dc:identifier.uri

http://hdl.handle.net/10339/39287

OAI identifier oai:identifier

oai:wakespace.lib.wfu.edu:10339/39287