Comparison of packed and wide-bore, open-tubular gas chromatographic columns

Wide-bore, fused-silica capillary columns can be an excellent replacement for packed columns in many cases. They can provide higher surface inertness and thermal stability, as well as higher efficiency or speed of analysis. Wide-bore, open-tubular (WBOT) columns with thick films have higher sample capacities than conventional narrow-bore capillary columns and can be used in unmodified packed-column gas chromatographs. The majority of gas chromatographic analyses are still performed using packed columns. Many chromatographers associate open-tubular columns exclusively with split injection, often perceived as less repeatable or quantitative. Also, many packed-column methods use application-specific stationary phases which are not readily available on capillary columns. WBOT columns with standard phases can often be substituted due to higher available efficiencies. While several studies have been published on qualitative differences, there is little comparative quantitative data available on O.53â mm I.D. and packed columns.

Name thesis:degree_name

Master of Science

Level thesis:degree_level

masters

Discipline thesis:degree_discipline

Chemistry

Department dc:contributor.department

Chemistry

Grantor dc:publisher

Virginia Tech

Year dc:date.issued

1987

Author dc:creator

• Shagena, Elizabeth C.

Chair dc:contributor.committeechair

• McNair, Harold M.

Committee members dc:contributor.committeemember

• Bell, Harold M.
• Long, Gary L.
• Hinshaw, J. V., Jr.

Statement dc:rights

• In Copyright

Licence dc:rights.uri

• http://rightsstatements.org/vocab/InC/1.0/

Dc Identifier Other

etd-11202012-040115

OAI identifier oai:identifier

oai:vtechworks.lib.vt.edu:10919/45896