Abstract
dc:description.abstractThe biosensing field has grown in importance and research efforts over the last few years for many reasons including point of care sensing devices and possible early detection of diseases in the body. Dopamine sensing is discussed in this paper and the development of a dopamine sensing platform would lead to early detection of diseases linked to its abundance or lack thereof in the brain such as Parkinson's disease. This work focuses on the electrochemical methods of biosensing, specifically dopamine sensing, and this method involves the use of electrodes as its sensing component. Multimaterial electrode-embedded fibers are used as the sensing electrode and the electrode material presented is platinum (Pt). Platinum is employed because of its biocompatibility property. The electrodes are placed in the fiber by the method of convergence fiber drawing and the fiber ends are stripped to expose the electrode for application. To make the proposed sensing platform more cost-effective, the platinum is electrodeposited onto the multimaterial fiber's embedded electrode. We discuss the use of a W/Pt modified electrode and a pure platinum wire in dopamine sensing and demonstrate that Pt is indeed a good candidate for dopamine sensing. The results show that the sensitivity of the W/Pt modified electrode to dopamine is higher than that of a pure Pt wire. This work has shown the promising application of electrodeposition in developing a cheaper flexible biosensing platform and opens up the possibility of the development of wearable flexible smart textile sensors because of the use of flexible multimaterial fibers.
Degree
thesis:*- Name thesis:degree_name
- Master of Science
- Level thesis:degree_level
- masters
- Discipline thesis:degree_discipline
- Electrical Engineering
- Department dc:contributor.department
- Electrical Engineering
- Grantor dc:publisher
- Virginia Tech
- Year dc:date.issued
- 2021
Author and committee
dc:creator, dc:contributor.*- Author dc:creator
-
- Alabi, Oluwademilade Adedunmolu
- Chair dc:contributor.committeechair
-
- Jia, Xiaoting
- Committee members dc:contributor.committeemember
-
- Zhou, Wei
- Zhu, Yizheng
Subjects
dc:subject × 6Rights
dc:rights- Statement dc:rights
-
- In Copyright
- Licence dc:rights.uri
Identifiers
dc:identifier.*- Dc Identifier Other
- vt_gsexam:31817
- OAI identifier oai:identifier
- oai:vtechworks.lib.vt.edu:10919/112992